Neurology: Genetics

Neurology® Genetics is an official journal of the American Academy of Neurology.



Vision: Neurology® Genetics will illuminate novel discoveries and be a leading resource in the field of human neurogenetics.



Mission: Neurology® Genetics will provide neurologists, geneticists, and neuroscientists with outstanding scholarly reports that elucidate the contributions of genetic and epigenetic variations to human neurologic disease, including the mechanisms of and therapeutic approaches to neurogenetic diseases.



Neurology® Genetics is an online open access journal publishing peer-reviewed reports in the field of neurogenetics. The journal publishes original articles in all areas of neurogenetics including:



Genetic drivers of disease:

Mendelian genetics

Non-Mendelian risk alleles

Genotype-phenotype correlations

Genetic epidemiology

Epigenetics

Disease mechanisms:

Transcriptome analysis

Pathway interrogation

Cellular investigations

Organ-level studies

Therapeutic development:

Preclinical studies

Natural history studies

Biomarker development

Human clinical trials

Post-marketing studies

We recognize that many manuscripts will cover more than one of these areas and our general expectation is that manuscripts convey a coherent narrative that includes a clinical or scientific question and a proposed answer based on the data collected and analyzed. We publish both human studies as well as in vitro and in vivo studies of model systems that are directly relevant to human neurogenetic disease.



Manuscripts relevant to all clinical areas of neurology across the lifespan are of interest, including but not restricted to epilepsy, inborn errors of metabolism, movement disorders, neurodegenerative disorders, neurodevelopmental disorders, neuromuscular disease, and vascular neurology/stroke.



Few single case reports will be considered, with rare exceptions that may include reports of a large single family with multiple affected individuals and reports that include data not readily available in a clinical setting. Any single case report or small case series must be formatted as a Clinical/Scientific Note.