Molecular Diagnosis of Deafness: Impact of Gene Identification.- Genetic Epidemiology of Deafness Genes and Clinical Applications.- Molecular auditory function.- Clinical Benefit of Molecular Diagnosis: Precision Medicine in Deafness.- Gap junction and channel transporter-related genes
.-
KCNQ4, GJB2, GJB6, KCNE1, KCNQ1, SLC26A4.- Stereocilia-related genes
CDH23, MYO7A, USH1C, PCDH15, USH1G, USH2A, ADGRV1, WHRN, CLRN1, MYO15A, MYO6, TMC1, STRC, ACTG1, DIAPH1, LOXHD1, PTPRQ, ESPN, MYO3A
.- Neurotransmission-related genes
OTOF, SLC17A8, PJVK
.- Transcription factor and related genes
EYA1, SIX1, PAX3, SOX10, MITF, SNAI2 CHD7, POU3F4, POU4F3, EYA4
.- Cell adhesion molecule and extracellular matrix-related genes
COL2A1, COL9A1, COL9A2, COL9A3, COL11A1, COL11A2, TECTA, OTOA, OTOG, OTOGL, COL4A3, COL4A4, COL4A5
.- Uncategorized important deafness genes
WFS1, COCH
,
TMPRSS3,
CRYM
,
NOG
, mitochondrial.- Cochlear Implantation from the perspective of the responsible gene.- Gene therapy and mechanism-based drugs: Toward more precise treatment based on molecular diagnosis.
