Role of Gut Microbiome in Neurodegenerative Disorders provides an overview of the gut microbiota and its interactions with the gut and the central nervous system. This book reviews the relevance of this axis to the pathogenesis of neurodegenerative diseases, such as Parkinson's disease (PD), Alzheimer's disease (AD), and Multiple sclerosis (MS). Various chapters discuss the effects of gut derived particles in various parts of brain and the targeting pathways leading to protein deposition in brain.
- Reviews the pathology and pathophysiology of gut derived neuropeptides in neurodegenerative disorders
- Discusses mechanism of gut derivatives on immune system
- Presents possible therapy mechanism using gut microbiome
 
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ISBN-13
978-0-443-29933-9 (9780443299339)
 
Schweitzer Klassifikation
 
 
1. Overview of Neurodegenerative Disorders2. Gut Microbiota and Neurological Diseases3. Gut-Brain Axis4. Gut-Brain Axis in Neurological Diseases5. Difference in the constitution of Gut Microbiota during Neurodegenerative Disorders6. Gut Metabolites in Neurodegenerative Diseases7. Influence of Gut Microbiota on Cerebellum8. Influence of Gut Microbiota on Hippocampus9. Influence of Gut Microbiota on Axonal Cells of the brain10. Mechanistic action of Gut Microbiota on Glial cells11. Gut as a second brain- Largest producer of serotonin12. Gradual Shift of gut microbial Population as a diagnostic marker for Neurodegenerative disorders13. Gut metabolites - effective biomarker for Neurodegenerative disorder14. Protocol - Isolation of Gut Microbiome from Faecal sample15. Gut metabolites isolation from Blood16. Metagenomics and sequence analysis17. Computer aided detection method18. Existing therapeutic options to alter gut composition in Neurodegenerative Disorders19. Dietary and Gut microbiome20. Ongoing clinical trials21. Ethical hurdles for the treatment of a disease focusing Gut Microbiota22. Futuristic therapies in pipeline for the betterment of Neurodegenerative Disorders