Microbial biofilms: Role in Human Infectious Diseases focuses on new and emerging concepts in microbial biofilm research, such as the mechanisms of biofilm formation, biofilm-induced pathogenesis, biofilm detection/and diagnosis, gene exchange within biofilms, strategies to control microbial biofilms and the burden of biofilm associated infections. In addition, it highlights the various anti-biofilm strategies such as surface coating, signal quenching, novel compounds that can be translated to curb biofilm-associated infections and the escalation of antimicrobial resistance determinants.
Microbial biofilms can be a serious problem in medical settings as they are associated with significant mortality and morbidity. Infection related to biofilms increases recovery time and the cost of disease management. Biofilms are resistant to known antibiotics and human defense mechanism. In addition, due to close proximity of microbes within biofilms, increase genetic transformation has been detected results in increases frequency of antibiotic gene spread. With the advancement in science and technology, novel strategies have been proposed to combat the impact of biofilms on human health.
- Fulfills the knowledge gap in biofilm study
- Focuses on new and emerging concepts in microbial biofilm research
- Highlights the various anti-biofilm strategies
- Provides concise, thorough and up-to-date information about the important role of microbial biofilms in human diseases
Sprache
Verlagsort
Verlagsgruppe
Elsevier Science & Techn.
Dateigröße
ISBN-13
978-0-443-19253-1 (9780443192531)
Schweitzer Klassifikation
1. Bacterial Biofilms and infectious disease in human health: a concise review2. Microbial biofilms: Role of biofilms in recurrent orthopaedic infections3. Dental biofilms: Application of nanoparticles to combat biofilms4. Streptococcus biofilms, and their role in human infectious diseases5. Surface coating: Strategy to prevent bacteria adhesion on medical implants6. Bacterial biofilm a major challenge in medical indwelling devices7. Single-species and multi-species biofilms causing infections8. Effects of environmental factors to promote formation of biofilms by respiratory pathogens9. Gut Microbiota: Role of biofilms in human health10. Antimicrobial/antibiotic resistance of biofilms and factors contributing to resistance11. Cell to cell interaction and cell signalling in biofilms12. Microbial biofilms and the skin microbiome13. Synthetic and phyto-compounds to combat microbial biofilms14. Next generation sequencing: Role in microbial biofilms study