Vestibular Schwannomas

Name: Vestibular Schwannomas
Brand: Elsevier
Price: 259.0 EUR
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Elsevier (Verlag)

Erschienen am 1. September 2025

500 Seiten

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978-0-323-85997-4 (ISBN)

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Beschreibung

Vestibular schwannomas are the most common tumors of the cerebellopontine angle (CPA), the junction between the cerebellum and the brainstem. They constitute around 8% of intracranial tumors. They are benign and arise from the vestibular nerve within the internal auditory canal growing from the canal into the CPA eventually causing brainstem compression. Their incidence is around 2.5 per 100,000. Around 70% of tumors do not grow following diagnosis but those that do or those that are already large at presentation are usually treated either with stereotactic radiosurgery or microsurgical resection.Vestibular schwannomas have been extensively investigated over the years with nearly 10,000 peer reviewed papers relating to them on Pubmed. Despite this plethora of data there are very few books that assimilate the literature to provide a comprehensive, readable and contemporary overview of their management. This book aims to meet these requirements covering both sporadic and neurofibromatosis type 2 vestibular schwannomas.The chapters within the book will cover all aspects of the diagnosis and management of vestibular schwannomas. Opening chapters provide a historical back drop, followed by current state of the art of molecular biology, histopathology and genomics relating to vestibular schwannomas. A comprehensive section related to the assessment of patients with vestibular schwannomas will highlight the multidisciplinary approach to the management of these tumors. This will set out some of the cutting edge research currently being undertaken in prediction of tumor growth using novel biological and radiological markers. The next section focuses on the treatment of vestibular schwannomas. This will make up the largest proportion of the book and will cover all treatment modalities from observation through to stereotactic radiosurgery and microsurgical resection. Lastly will be a section focusing on rehabilitation of neurological deficit arising as a result of the disease or its treatment. - Consolidates best practice on diagnosis and treatment of vestibular schwannomas - Includes both sporadic and neurofibromatosis type 2 vestibular schwannomas - Covers stereotaxic radiosurgery and microsurgical resection - Discusses molecular biology, histopathology and genomics - Presents rehabilitation for neurological deficits resulting from schwannomas and treatment

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1. History of¿vestibular schwannoma managementSection I. Basic Science 2. Applied anatomy in vestibular schwannoma3. Molecular biology and disease models of vestibular schwannomas: State of the art4. Pathology and tumor microenvironment of vestibular schwannoma5. Genomics of vestibular schwannoma6. Vestibular schwannomas: Key research questions and prioritiesSection II. Assessment 7. Clinical evaluation and investigation of patients with a sporadic vestibular schwannoma8. Clinical evaluation and investigation of vestibular schwannoma in NF2-related schwannomatosis9. Vestibular schwannoma imaging and differential diagnosis10. Clinical epidemiology of sporadic vestibular schwannomas11. Clinical epidemiology of NF2-related schwannomatosisSection III. Treatment 12. Surveillance management of vestibular schwannoma: present and future strategies13. Medical therapy for vestibular schwannomas14. Translabyrinthine approach to the cerebellopontine angle15. Retrosigmoid approach to vestibular schwannoma16. Middle fossa approach to vestibular schwannomas17. The retrolabyrinthine approach18. Endoscopic vestibular schwannoma surgery19. Vestibular schwannoma microsurgical technique20. Outcomes following vestibular schwannoma surgery21. Salvage resection and radiosurgery following failed primary treatment of vestibular schwannomas22. Hearing preservation surgery for vestibular schwannoma23. Vestibular schwannoma, postsurgical complications24. Anesthesia for excision of vestibular schwannomaSection IV. Stereotactic radiosurgery for vestibular schwannomas 25. Gamma knife radiosurgery for vestibular schwannomas26. LINAC stereotactic radiosurgery for vestibular schwannomas27. Fractionated radiotherapy for vestibular schwannoma28. Proton therapy for vestibular schwannomasSection V. General Considerations 29. Decision making in sporadic VS30. Decision making in neurofibromatosis type 231. Management of vestibular schwannoma in the elderly32. Subtotal versus total excision of vestibular schwannomas33. Quality of life after treatment of vestibular schwannomas34. The role of the clinical nurse specialist in managing vestibular schwannoma35. Vestibular schwannoma: Global perspectivesSection VI. Rehabilitation 36. Secondary trigeminal neuralgia due to vestibular schwannoma37. Hearing rehabilitation in patients with vestibular schwannomas38. Prevention and rehabilitation of facial palsy in patients with vestibular schwannomas39. Dizziness in vestibular schwannomas40. Tinnitus and its management in patients with vestibular schwannoma

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