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This book aims to present the latest research on drug delivery systems. It summarizes emerging drug delivery strategies and new technologies for cancer treatment, viewed through the lens of cancer pathology. Topics include immunotherapy strategies, biomimetic drug delivery strategies, live cell drug delivery strategies, nanocrystal technology, and 3D printing technology. The book is intended for researchers, R&D engineers, and graduate students in the pharmaceutical field. Additionally, it is expected to inspire collaboration among experts from different disciplines to advance the development of drug delivery systems.
Dr. Lesheng Teng holds an academic appointment of Professor at Jilin University. His research is focused on a highly interdisciplinary combination of nanotechnology, biomaterials, drug delivery, and immunotherapy. He has developed various nanoparticle platforms for delivery of small molecules, proteins, and nucleic acids (e.g., siRNA and mRNA). He has published over 120 peer-reviewed papers and holds over 20 patents/patent applications. Representative papers were published in Nature Biomedical Engineering, Nano Letters, Biotechnology Advances, ACS Applied Materials & Interfaces, Journal of Controlled Release, Theranostics and Nanoscale. He has also received many awards, such as excellent supervisor, and others. Dr. Teng obtained his BS degree and PhD degree from Jilin University.
Dr. Zhaogang Yang is an assistant professor in the Department of Radiation Oncology, UT Southwestern Medical Center. Dr. Yang received his B.S. in Pharmaceutical Sciences (2003) and M.S. in Pharmaceutics (2006) from Peking University, China. Then, he completed his M.S. in Pharmacology (2010) and Ph.D. in Pharmaceutical Sciences (2012) at the Ohio State University, USA. He served as a post doctor in Mayo Clinic in Rochester for 1 year (2013), and a research associate at the Ohio State University for 6 years (2013-2019). Dr. Yang's research interests focus on the application of nanotechnology in drug delivery, including novel nanoparticle-based cancer detection, gene delivery and cancer therapy, and nanoelectroporation in gene therapy. He has authored 4 book chapters, more than 80 peer-reviewed journal papers, 7 conference abstracts, and 2 patents. He is a consultant editor of "International Journal of Nanomedicine". In addition, he is the Guest Editor for "Current Organic Chemistry", "Dose-Response " and "Molecules" special issues.
Chapter 1 Cancer Biology and Microenvironment.- Chapter 2 Development and advantages of drug delivery systems.- Chapter 3 Drug Delivery Strategies That Target Tumors.- Chapter 4 Combined Therapy in Cancer Treatment.- Chapter 5 Prodrug Nanocarrier.- Chapter 6 Smart drug delivery vehicle.- Chapter 7 Cell Derived/Bionic-Drug Delivery Vehicles.- Chapter 8 Cellular drug delivery vehicle.- Chapter9 Nanocrystal technology.- Chapter 10 Application of Microneedles in Anti-tumor Therapy.
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