1. Introduction to "inoperable gliomasIsaac Yang, Carlito Lagman, Giyarpuram N. Prashant, Thien Phuc Nguyen and John Patrick Sheppard2. The ethics of brain tumor "inoperabilityMichael E. Sughrue3. Connectomic imaging for neurosurgeonsMichael E. Sughrue4. Network anatomy of the brainMichael E. Sughrue5. Techniques for tackling difficult gliomasMichael E. Sughrue6. Advances in the surgical treatment of speech-eloquent gliomasNathan Kong and Matthew Tate7. Insular gliomasMichael E. Sughrue8. Advances in the surgical resection of temporoparietal-occipital junction gliomasIsaac Yang and Giyarpuram N. Prashant9. Surgical techniques for motor eloquent gliomasMichael E. Sughrue10. Butterfly glioma resection: Surgery around the initiation axisMichael E. Sughrue11. Thalamic gliomas: Advances in the surgical managementMichael Lim and Alice Hung12. Essentials to planning a brainstem caseChad A. Glenn, Michael E. Sughrue and Charles Teo13. The role of adjuvant therapies in "inoperable gliomasGordon Li, David Dadey and Kevin Chow14. The role of adjuvant therapies in "inoperable gliomasMichelle A. Wedemeyer and Gabriel Zada15. Laser interstitial thermal therapy for "inoperable gliomasDaniel Eichberg, Ashish Shah and Michael E. Ivan