Marine Biotechnology

Preface xiii

1 Marine Biotechnology: Studies and Applications-Stateof-the-Art and New Challenges 1
Shaju S. S., Vipin. P. M., Visakh. P.M. and Shiv Kumari Panda

1.1 Exploring the Therapeutic Potential of Microalgae-Derived Compounds 2
1.2 Pharmaceutical and Nutraceutical Applications of Marine Microalgae 3
1.3 Extraction of Drugs and Food Ingredients from Marine Macroalgae 5
1.4 Biotechnological Applications of Marine Bacteria: Marine Biotechnology 6
1.5 Nanoparticles and Phytoconstituents from Marine Mangrove Plant 8
1.6 Mesopelagic Fish Protein Hydrolysates 9
1.7 Mesopelagic Fishes: Potential Use for Anticancer and Antimicrobial Biotechnological Applications 11
1.8 Marine-Derived Drugs: Recent Advances in Cancer Therapy and Immune Signaling 12
1.9 Marine Bivalve-Derived Bioactive Compounds: Anticancer and Antimicrobial Effects 13

2 Exploring the Therapeutic Potential of Microalgae-Derived Compounds: Commercial Significance, Advanced Cultivation Methods, and Life Cycle Analysis 25
Vishnu K. Venugopalan, Lekshmi R.G. Kumar, Paras Nath Jha, Vishnuja Soman, A. A. Mohamed Hatha and S.S. Shaju

2.1 Introduction 26
2.2 Microalgae as Source of Nutrients 27
2.3 Extraction Methods 31
2.4 Commercially Important Microalgae 35
2.5 Cultivation Methods 37
2.6 Economic Importance 42
2.7 Life Cycle Assessment 42
2.8 Challenges and Future Prospects 43
2.9 Conclusion 43

3 Pharmaceutical and Nutraceutical Applications of Marine Microalgae 53
Nayomi John, Parvathy Raj, Jinsa Jose, Swathy T., Fathima Ferin Haneef, Gokuljith S. and Rukkiya Sunil

3.1 Introduction 53
3.2 Marine Microalgae 57
3.3 Marine Phytoplankton 64
3.4 Pharmaceutical Applications of Marine Microbiology 69
3.5 Nutraceutical Application of Marine Microalgae (Phytoplanktons) 80
3.6 Conclusion 86

4 Extraction of Drugs and Food Ingredients from Marine Macroalgae 111
P. Ruban, Vinitha Ebziba C., K. Ramalashmi, S. Arul Diana Christie, Mohammed Rafiqkhan K. and Kavitha M.B.

4.1 Introduction 112
4.2 Marine Macroalgae 114
4.3 Classification of Marine Macroalgae 115
4.4 Extraction of Drugs from Marine Macroalgae 119
4.5 Extraction of Food Ingredients from Marine Macroalgae 127
4.6 Conclusion 134

5 Biotechnological Applications of Marine Bacteria: Marine Biotechnology 139
Nayomi John, Anjala Shirin, Roby K. Mathew, Muhammed Faiz, Sneha P. Thomas, Fathima Safa and Lena Joseph

5.1 Introduction 140
5.2 Marine Bacteria 145
5.3 Biotechnological Applications of Marine Bacteria 153
5.4 Conclusion 162

6 Nanoparticles and Phytoconstituents from Marine Mangrove Plant: Potential for Biochemical Applications 169
Divya Kumari and Pracheta Janmeda

6.1 Introduction 170
6.2 Marine Mangrove Plant 171
6.3 Nanoparticles from Marine Mangrove Plant 173
6.4 Phytoconstituents from Marine Mangrove Plant 180
6.5 Biochemical Applications 181
6.6 Conclusions 186

7 Mesopelagic Fish Protein Hydrolysates: A Source of Antihypertensive and Antidiabetic Peptides 197
Hilary Kwesi Ketemepi, Sharifudin Md. Shaarani and Nor Qhairul Izzreen Mohd Noor

7.1 Introduction 198
7.2 Mesopelagic Fish Protein Hydrolysates 207
7.3 Mesopelagic Fish Protein Hydrolysates: Antihypertensive Peptides of Pelagic Fish Protein Hydrolysates 213
7.4 Mesopelagic Fish Protein Hydrolysates: Antidiabetic Peptides 222
7.5 Conclusion 229

8 Mesopelagic Fishes: Potential Use for Anticancer and Antimicrobial Biotechnological Applications 239
Divya Kumari and Pracheta Janmeda

8.1 Introduction 240
8.2 Mesopelagic Fishes 241
8.3 Mesopelagic Fishes: Potential Use for Anticancer Applications 243
8.4 Mesopelagic Fishes: Potential Use for Antimicrobial Applications 244
8.5 Notable Mesopelagic Fishes with Anticancer and Antimicrobial Properties 245
8.6 Conclusions 255

9 Marine-Derived Drugs: Recent Advances in Cancer Therapy and Immune Signaling 261
Dhanisha Sulekha Suresh

9.1 Introduction 261
9.2 Marine-Derived Drugs 263
9.3 Marine-Derived Drugs: Recent Advances in Cancer Therapy 267
9.4 Marine-Derived Drugs: Recent Advances in Immune Signaling 273
9.5 Exploring Advancements and Hurdles in Marine Pharmaceutical Research 277
9.6 Conclusions 278

10 Marine Bivalve-Derived Bioactive Compounds: Anticancer and Antimicrobial Effects 287
Suna Bekta?, Nahdhoit Ahamada Rachid, Önder Kilic and Serap Sancar

10.1 Introduction 288
10.2 Bioactive Molecules from Marine Bivalves 289
10.3 Conclusion 305

References 306
Index 315