Nanotheranostics and Precision Oncology delves into the merging fields of cancer research and nanotechnology, offering a thorough review of the latest advancements in precision oncology. It begins with an exploration of cancer biology, illuminating the genetic foundations of oncogenesis alongside the cellular and molecular mechanisms driving cancer progression, metastasis, and drug resistance. This resistance remains the foremost challenge in cancer care. Across 28 chapters, the book addresses precision medicine's role in overcoming drug resistance, the importance of biomarkers, the interpretation of genetic analyses, and the shift toward personalized oncology.In addition, the book examines nanotheranostics' applications and mechanisms in cancer diagnosis and treatment, integrating them with precision oncology. It outlines the design, mechanism, and impact of nanoprecision medicine in cancer management. The final section considers the future of nanotheranostics in precision oncology and the challenges of translating these innovations from research to clinical practice. This comprehensive guide serves students, clinicians, researchers, and the pharmaceutical industry involved in nanomedicine, oncology, molecular biology, and precision medicine.
- Offers a comprehensive look at cancer biology and the genetic roots of oncogenesis
- Provides in-depth coverage of the latest in precision oncology and nanotheranostics, including development and clinical use
- Explores the integration of nanotechnology with precision medicine for creating individualized treatments
- Includes case studies and regulatory insights that guide pharmaceutical innovation and clinical practice
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ISBN-13
978-0-443-34672-9 (9780443346729)
Schweitzer Klassifikation
Section I: Cancer Biology1. Oncogenesis: Genetic Basis2. Hallmarks of cancer3. Cancer Stem Cells and Tumor Microenvironment4. Mechanisms Underpinning Invasion and Metastasis5. Drug Resistance and CancerSection II: Precision Oncology6. Introduction to Precision Medicine o of precision medicine's history, components, and milestones.7. Translational Bioinformatics & Precision Medicine8. Proteomics, Metabolomics and Precision Medicine9. Biomarkers and Circulating DNAs as Predictive Molecular Signatures10. Genomic Strategies for Precision Medicine11. Immunotherapy as a Tool of Precision Medicine12. Clinically Approved and Under-Trial Drugs for Precision OncologySection III: Nanotheranostics13. Introduction to Nanotheranostics14. Active and Passive Targeting of Nanoparticles15. Nanocontrasts, Nanoprobes, and Nanosensors in Cancer Diagnosis16. Nanoparticles as Delivery Vehicle for Drugs and Genes17. Nanoparticles for Thermal Ablation o Exploring novel nanoparticle-mediated cancer therapies.Section IV: Designing Nanotheranostics for Precision Medicine18. Current Status of Nanotheranostics in Precision Medicine19. Nanoimmunotherapy20. Stimuli Responsive Nanotheranostics for Precision Medicine21. Pharmacogenomics-Based Nanoprecision Medicine22. ADME of Nano-Precision MedicinesSection V: Challenges and Future Potentials23. Challenges in Translation of Nanoprecision Medicine24. Ethical and Legal Considerations in Use of Nanotheranostic and Precision Medicine25. Economic Challenges in Use of Nanotheranostics and Precision Medicine26. Biomarkers That Could be Born Because of Nanotheranostics and Precision Medicine27. Panomics, Artificial Intelligence, and Precision Medicine28. Mirage of Nanotheranostics and Precision Medicine: Future Implications
