Features, Transmission, Detection, and Case Studies in COVID-19 examines the effects of the virus on the body, as well as its transmission and clinical profile. This volume begins with an introduction to the virus and its pathogenesis, transmission, and avoidance, followed by sections on pulmonary and cardiovascular effects, obesity, diabetes, the liver, detection issues, and biomarkers. Vaccines and treatment are also discussed. Specific case studies covered include hypoxia, acute kidney injury, pneumonia, and neurological effects. This volume is relevant for all clinicians and scientists working to ensure the best outcomes for patients with COVID-19.
- Discusses COVID-19 biology, including pathogenesis and transmission
- Describes systemic issues caused by COVID-19, including cardiovascular effects and loss of taste and smell
- Outlines detection methods, biomarkers associated with severity, and disease outcomes
- Features individual chapter introductions, summaries, and case studies to provide comprehensive descriptions of COVID-19 symptoms and effects
- Contains chapters with key facts, dictionary of terms, summary points, applications to other areas pertinent to each chapter, and policies and procedures
Sprache
Verlagsort
Verlagsgruppe
Elsevier Science & Techn.
Dateigröße
ISBN-13
978-0-323-95647-5 (9780323956475)
Schweitzer Klassifikation
Section A: SARS-CoV-2 and COVID-19: Introductory chapters and setting the scene1. Coronavirus disease 2019 (COVID-19) pandemic in context: Systemic effects2. Early warning of SARS-CoV-2 infection3. Mobile phones and their use to study dynamics of the COVID-19 pandemicSection B: Structure, transmission and avoidance4. Cis regulatory elements: A novel communication route between the host cell and the SARS-CoV-2 genome5. SARS-CoV-2 ORF8: Structure, evolution, molecular function, and its contribution to thepathogenicity of the virus6. SARS-CoV-2 spike protein binding ligands and its application in COVID-19 therapeutics7. SARS-CoV-2 bulldozes the autophagy pathway and unhinges mitochondrial quality controlthereby driving neurodegeneration-A hypothesis8. The Omicron variant of SARS-CoV-29. Monitoring SARS-CoV-2 spread in hospitals10. Computational analysis of mutations in SARS-CoV-2 variants spike protein and proteininteractions11. Airborne transmission of SARS-CoV-212. Reducing transmission of SARS-CoV-2 with face masks: Its potential protective effects13. Digital twin of ventilation system against COVID-19 transmission and infection risk14. Pets and SARS-CoV-2: What is their role in the epidemiology of the disease?15. SARS-CoV-2 transmission in dental practice16. SARS-CoV-2 compared with influenza and respiratory syncytial virus in terms of verticaltransmission17. Reducing droplets and aerosols in the surgical setting and applications to the COVID-19pandemic18. SARS-CoV motion dynamics: Linking in droplet size19. Ventilation and airborne particles in classrooms: Implications for the COVID-19 pandemic20. Indoor transmission of the SARS-CoV-2 virus through aerosols emitted by e-cigarettesSection C: Impact and effects21. The Impact of COVID-19 on first responders22. COVID-19 and suspected drug-induced liver injury23. Pulmonary fibrosis in COVID-1924. The effect of SARS-CoV-2 infection on cancer: Clinical correlation andpotential pathological mechanism25. Severe SARS-CoV-2, plateletendothelium interactions, and cardiovascular injury26. Cardiometabolic syndrome and COVID-19: Pathophysiological aspects27. COVID-19 and type 1 and 2 diabetes: An overview28. COVID-19 and older adults: An overview29. COVID-19 and male fertility30. COVID-19 and obesity: An overviewSection D: Treatments, strategies, and vaccines31. COVD-19 vaccines and their impact: An overview32. Exploring the promise of COVID-19 vaccines: A review of preclinical studies33. Drugs actively being investigated for use in COVID-1934. The biology of neutralizing antibody therapy with REGEN-COV35. The intensive care unit and percutaneous tracheostomy in patients with coronavirus disease201936. Cardiac effects of drugs and vaccines used to treat and prevent COVID-1937. COVID-19 pandemic and isolation: Impact on sleep38. Strategies in the COVID-19 pandemic: Disinfection of gloved hands39. In silico studies on established antivirals on SARS-CoV-2 RNAdependent RNA polymerase40. The COVID-19 cytokine storm and its immunomodulatory treatment41. Safety and efficacy of nebulization for reducing the intensity of viral load and clinical manifestations in patients with COVID-19Section E: Detection and biomarkers42. Bronchoalveolar lavage (BAL) and use in detection of SARS-CoV-243. SARS-CoV-2 testing and vaccination among people who use drugs44. Homocysteine as a biomarker in COVID-1945. Assessment of smell and taste in COVID-1946. S-gene analysis: RT-PCR and Sanger sequencing applied to SARS-CoV-2 virus47. False-negative results in screening for SARS-CoV-248. Sample pooling and SARS-CoV-2 assays49. Biomarkers of invasive mechanical ventilation in obesity and metabolic syndrome in patientswith COVID-19Section F: Case studies with mini review50. Hypoxia and heart-lung interactions in COVID-19: The significance of right heart dysfunction and shunt51. Ulnar nerve dysfunction as COVID-19 sequelae52. Case study: Coronavirus disease 2019 and acute kidney injury53.
