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Breast cancer cases are increasing rapidly with high mortality rates. Microwave imaging is emerging as a new diagnostic option because it can overcome the disadvantages of X-ray based mammography.
The reference text explores breast cancer, microwave scattering and microwave imaging based cancer detection as well as role of machine learning and artificial intelligence in the breast cancer diagnosis. Breast anatomy and breast cancer types are covered to understand the severity of breast cancer. Different breast screening techniques are then described along with their advantages and disadvantages. The problem of multiple frequency inverse scattering is formulated and the whole microwave breast imaging system is converted into matrices for easy manipulations and optimization.
In the second section of the book 3-D level set based optimization is discussed. Following an introduction this is described by using single and double level set functions. Ill-posed and noisy measurements are two main problems in the 3-D level set based optimization. These two problems are addressed by using Tikhonov and total variation (TV) regularization schemes.
Finally, advanced methods in image reconstruction techniques are explored. Electric field integral equation is solved in method of moments with detailed derivations. Machine learning-based advanced methods are then described for breast cancer detection.
The key audience for this reference text includes industries working in the areas of breast cancer imaging, prostate cancer imaging, medical image segmentation and machine learning.
Key features:
Dr Hardik N. Patel completed his PhD from Dhirubhai Ambani Institute of Information and communication technology in 2019. Master of Technology in Communication Systems from Sardar Vallabhbhai National Institute of Technology in 2010. He has completed his B.E. in electronics and communication from Sardar Patel University in 2007. He was Associate System Engineer in IBM India Pvt. Ltd. from 2010 to 2011. He is working as an assistant professor in Pandit Deendayal Energy University since 2020. His research interests are machine learning, AI for imaging and cancer detection, health analytics, image and video analytics, communication and signal processing, Autonomous driving.
Dr Deepak K. Ghodgaonkar received his Bachelor of Engineering in Electronics Engineering from the University of Indore in 1976, Master of Technology in Electrical Engineering, Communication Engineering from IIT Bombay in 1978 and Doctorate in Electrical Engineering from the University of Utah, USA in 1987. He has more than 30 years of teaching and research experience and has published over 150 publications in the form of Books, Book Chapters, Journal Papers, Conference Papers, Edited Conference Proceedings and Research Reports.
Dr Jasjit S. Suri has spent over 30 years in the field of biomedical engineering/sciences, software and hardware engineering and its management. He received his Masters from University of Illinois, Chicago and Doctorate from University of Washington, Seattle. Dr. Suri was crowned with President's gold medal in 1980, one of the youngest Fellow of American Institute of Medical and Biological Engineering (AIMBE) for his outstanding contributions at Washington DC in 2004 and was also a recipient of Marquis Life Time Achievement Award for his outstanding contributions in 2018.
1 Introduction to Breast Cancer 1.1 Introduction to Cancer 1.2 World Wide Cancer Statistics 1.3 Breast Cancer Statistics 1.3.1 Breast Cancer Prediction 1.4 Breast Anatomy and Breast Cancer Bibliography2 Introduction to Breast Cancer Detection Techniques 2.1 Imaging Modalities for Breast Cancer Screening2.2 Mammography 2.2.1 History of Mammography 2.2.2 Basic Understanding of Mammography 2.2.3 Advantages and Disadvantages of Mammography 2.3 Ultrasound Imaging 2.3.1 History of Ultrasound 2.3.2 Physics of Ultrasound 2.3.3 Current Status of Ultrasound Imaging2.3.4 Advantages and Disadvantages of Ultrasound2.4 Magnetic Resonanace Imaging2.4.1 Short History of MRI2.4.2 Working Principle of MRI2.4.3 Advantages and Disadvantages of MRI2.5 Positron Emission Tomography 2.5.1 Short History of PET 2.5.2 Advantages and Disadvantages of PET2.6 Diffuse Optical Tomography2.6.1 Short History of Optical Tomography 2.6.2 Advantages and Disadvantages of Diffuse optical tomography 2.7 Electrical Impedance Tomography2.7.1 Advantages and Disadvantages of EIT2.8 Computed Tomography (CT)2.8.1 Short History of CT2.8.2 Advantages and Disadvantages of CT 2.9 Microwave Imaging 2.9.1 Passive Microwave Imaging2.9.2 Active Microwave imaging2.10 Comparison of Mammography, MRI and Ultrasound 2.11 Overview of Image Reconstruction Methods 2.11.1 Algebraic Reconstruction2.11.2 Analytic Reconstruction 2.11.3 Statistical Reconstruction2.11.4 Learned Iterative Reconstruction Bibliography3 Introduction to Microwave Imaging 3.1 Introduction 3.2 Introduction to Passive Microwave imaging3.2.1 Emission Principles 3.2.2 Radiative Transfer3.2.3 Bio-Heat Transfer 3.2.4 Temperature Resolution 3.3 Microwave Radiometry for Cancer Detection3.3.1 Multi Probe Radiometric Imaging 3.3.2 Multi Frequency Microwave Radiometry3.4 Active Microwave Imaging Bibliography4 Finite Difference Time Domain Method for Microwave Breast Imaging 4.1 Overview of Computational Electromagnetic 4.1.1 Low Frequency Methods 4.1.2 High Frequency Methods 4.2 Motivation 4.3 Overview of FDTD 4.4 Derivation of Basic FDTD Update Equations4.5 Polarization Current Density Equation Derivation for Numerical Breast Phantom Region 4.6 Electric Field Update Equation Derivation for Numerical Breast Phantom Region 4.7 Derivation of Electric Field Update Equations for PML Region 4.8 Magnetic Field Update Equations 4.9 Steps for FDTD Implementation 4.10 Simulation Parameters 4.11 Results 4.12 Summary Bibliography5 3D Level Set based Optimization 5.1 Multiple Frequency Inverse Scattering Problem Formulation5.2 Introduction 5.3 Problem Formulation 5.4 Review of Previous Work 5.5 Theoretical Foundations 5.5.1 Evolution Approach5.5.2 Optimization Approach 5.6 Single 3D Level Set Function based Optimization 5.7 Two 3D Level Set Function based Optimization 5.7.1 3D Level Set based Regularized Optimization 5.7.2 Steps for 3D Level Set based Optimization Implementation 5.8 Simulation Parameters 5.9 Results Bibliography6 Method of Moments 6.1 Theoretical Background6.2 Problem Formulation6.3 Computation Reduction using Group Theory6.3.1 Human Breast Models 6.3.2 Symmetry Exploitation using Group Theory 6.4 Inverse Scattering Problem Formulation 6.5 Simulation Parameters and Noise Consideration 6.6 Results Bibliography 7 Finite Difference Time Domain For Microwave Imaging 7.1 Introduction to Finite Difference Time Domain7.1.1 Grid Size and Stability 7.1.2 Input Wave for Yee Grid Computations 7.1.3 Two Dimensional FDTD Analysis of Microwave Breast Imaging 7.1.4 Healthy Breast Tissue Dielectric properties 7.1.5 Design of Antenna Array 7.2 Microwave Image Formation using Confocal Technique 7.3 Space-Time Beamforming7.4 Removal of skin-breast artifact 7.5 FDTD based Time Reversal for Microwave Breast Cancer Detection 7.5.1 Matched filter FDTD based time reversal Bibliography8 Review of Machine Learning based Image Reconstruction for different Imaging Modalities 8.1 Introduction8.1.1 Image Reconstruction (Inverse) Problem Formulation 8.2 Traditional Image Reconstruction Techniques 8.3 Machine Learning Techniques for Image Reconstruction 8.3.1 Machine laerning based solution of inverse problems8.3.2 Machine learning in computed tomography8.3.3 Physics of low-dose X-ray CT8.4 Performance Analysis of Proposed ApproachesBibliography 9 Review of Machine learning based image reconstruction for microwave breast imaging9.1 Motivation 9.2 Machine Learning in Microwave imaging9.2.1 Current challenges in microwave breast diagnosis systems9.2.2 Challenges in the development of robust machine learning classification models9.3 Flow of the machine learning based microwave breast imaging for cancer diagnosis9.3.1 Data collection through microwave scanning 9.3.2 Data Processing 9.3.3 Diagnosis 9.4 Variational bayesian inversion for microwave breast imaging 9.5 Deep Neuarl Networks for microwave breast imagingBibliography 10 Microwave Image Reconstruction Methods10.1 Levenberg-Marquardt Method 10.1.1 Forward Problem10.1.2 Inverse Problem Solution by using Levenberg-Marquardt10.1.3 Choice of the Regularization Parameter10.2 Gauss-Newton Method10.2.1 Forward Problem Formulation10.2.2 The Inverse Problem Formulation 10.2.3 Gauss-Newton Optimization in General10.2.4 Gauss Newton Method for the Least Squares 10.2.5 The BFGS Quasi-Newton Method10.3 Born Iterative Method10.4 Stouchastic Optimization Methods for Microwave Imaging10.4.1 Genetic AlgorithmBibliography 11 The Role of AI in Diagnosis, Treatment and Monitoring of Breast Cancer during COVID19 and ahead 11.1 Introduction11.2 AI Architectures11.3 The Role of Artificial Intelligence in Diagnosis of Breast Cancer 11.4 The Role of Artificial Intelligence in Treatment of Breast Cancer11.5 The Role of Artificial Intelligence in Monitoring of Breast Cancer 11.6 AI Based Integrated System for Breast Cancer Management Bibliography
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