Physico-Chemical Aspects of Dosage Forms and Biopharmaceutics: Recent and Future Trends in Pharmaceutics, Volume Two explores aspects of pharmaceutics with an original approach that focuses on technology, novelties and future trends. The field of pharmaceutics is highly dynamic and rapidly expanding day-by-day, so it demands a variety of amplified efforts for designing and developing pharmaceutical processes and formulation strategies. Readers will find practical information for conducting research in pharmaceutics that is ideal for researchers in academia and industry as well as advanced graduate students in pharmaceutics.
In addition, the book discusses the most recent developments in biopharmaceutics, including important and exciting areas such as solubility of drugs, pharmaceutical granulation, routes of drug administration, drug absorption, bioavailability and bioequivalence.
- Provides extensive details on the most recent developments in biopharmaceutics
- Contains contributions from leading experts from academia, research, industry and regulatory agencies
- Includes high quality illustrations, flow charts and tables for easier understanding of the concepts
- Discusses practical examples and research case studies
Sprache
Verlagsort
Verlagsgruppe
Elsevier Science & Techn.
Dateigröße
ISBN-13
978-0-323-97247-5 (9780323972475)
Schweitzer Klassifikation
Section I: Physico-chemical aspects of dosage forms1. Physico-chemical factors influencing drug degradation2. Stability and accelerated stability studies of dosage forms3. Solubility of drugs4. Drug dissolution studies of pharmaceutical formulations5. Pharmaceutical granulation: Engineering perspective and futuristic trends6. Tablet compression and consolidation: Theory and applicationsSection II: Biopharmaceutics7. Introduction to Biopharmaceutics8. Gastrointestinal absorption of drugs9. Routes of drug administration and their impact in biopharmaceutics10. Drug elimination and renal excretion of drugs11. Membrane transport and permeation of drugs12. Factors affecting drug absorption and disposition13. Bioavailability and bioequivalence14. Contribution of biopharmaceutics and pharmacokinetics to improve drug therapy15. Dosage regimen16. Multicompartment models17. Nonlinear pharmacokinetics18. Computer-aided biopharmaceutical model development19. Computer simulations in pharmacokinetics20. WHO and ICH Guidelines for 'Good Manufacturing Practices'21. Pilot plant scale up techniques in pharmaceutical product development22. Advances in solid dosage forms
