Cannabis and Khat in Drug Discovery

Part A: Introduction1. Introduction to Catha edulis and Cannabis2. Ethnomedicinal uses of cannabis3. Ethnomedicinal uses of Catha edulis4. Cannabis chemotypes: sativa, indica, and others5. Cannabinoids and their subclasses - Lucia Kabanga6. The Chemistry and Pharmacology of Tetrahydrocannabinol and Cannabidiol7. Cannabis infused foods: Efficacy, safety and regulation8. Water resource demands and management in the growth of cannabis industrializationPart B: Chemical analyses and bioassays1. Extraction and isolation of cannabinoids2. Chromatographic fingerprinting and spectroscopic profiling of cannabinoids3. Antiviral properties of cannabidiol (CBD)4. In vitro and in vivo assays and safety profiles of cannabinoids5. In vitro and in vivo toxicology of cannabinoids6. Immunomodulatory properties of cannabis7. Pharmacologically active ingredients from Catha edulis8. Phytochemistry of Catha edulis9. In vitro and in vivo assays and toxicity profile of Catha edulis10. Physicochemical properties of Catha edulis11. Cannabis and reproductive physiologyPart C: Medicinal Chemistry, Chemical Biology and Pharmacology1. Cannabinergics2. Medicinal Chemistry of cannabinoids and endocannabinoids3. Biosynthesis of cannabinoids and endocannabinoids4. Cannabinoid ligands and receptors5. Medicinal Chemistry of selected active compounds in Catha edulis6. Catha edulis, Cannabis and the nervous system7. Structural analysis of Catha edulis's sympathomimetric amines to amphetamine and adrenaline8. Stimulants from Catha edulis9. Catha edulis and concomitant drug bioavailability10. Interactions of Catha edulis agents with CB2 receptors11. In Silico Drug Design Studies of Bioactives in Catha edulis, Cannabis, and their derivativePart D: Catha edulis and cannabinoids in disease management; Clinical aspects Prologue to part D 1. Cannabis in pain management2. Cannabinoids in cancer management3. Cannabis in antimicrobial drug development4. Cannabis in fungal infection management5. Cannabis in Post-traumatic stress disorder management6. Cannabis use in Unani Medicinal practices7. Catha edulis in antimicrobial drug development8. Dependence syndrome in Catha edulis product uses9. Catha edulis in pain management10. Catha edulis and type 2 diabetes mellitus11. Catha edulis in the management of cancers12. Clinical uses of cannabis and Catha edulis products13. Cannabinoid therapy and concomitant administered agents14. Dependence syndrome in cannabis product uses15. Hepatocellular injury from Catha edulis16. Innovative cannabis products on the market17. Pestcides and disease causing contaminants in Khat and khat productsPart E: Policy and regulations1. Industrial and medical use approvals and regulations of Cannabis products2. Conservation of Cannabis species and their products3. Policy and Regulation of Catha edulis product uses4. Future perspectives on the use of cannabis and Catha edulis products