Biomaterials for Advanced Drug and Therapeutic Delivery provides a detailed review of a range of biomaterials for drug delivery, gene, vaccine and therapeutics delivery, and wound healing and tissue regeneration. Divided into 5 sections, this book begins with an introduction to biomaterials for biomedical applications before systematically detailing advances in each application. A wide selection of biomaterials are covered, including nanobiomaterials, biopolymers, hydroxyapatite, lipid-based biomaterials, proteins, and more. In addition, the properties and characteristics of each biomaterial type is assessed, along with it's suitability for a range of drug delivery and therapeutic applications.The final section of the book provides insight into the safety, biocompatibility, preclinical and regulatory aspects of biomaterials use, exploring the translational potential of these novel materials and treatments. This book will be of use to researchers and academics in the fields of materials science, biomaterials, pharmaceutical science, and regenerative medicine.
- Explores the safety, biocompatibility, preclinical, and regulatory aspects of biomaterials' use for drug delivery and therapeutics
- Details a wide range of biomaterial types, from synthetic polymers and biopolymers to nanobiomaterials and peptides
- Utilizes an interdisciplinary approach, bringing together insights from materials science, pharmaceutical science, and regenerative medicine
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978-0-443-26658-4 (9780443266584)
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SECTION 1: BIOMATERIALS - AN OVERVIEW 1. Overview of biomaterials in biomedical applicationsSECTION 2: BIOMATERIALS FOR DRUG DELIVERY1. Medium chain triglycerides and fractions in drug delivery systems2. Nanostructured lipid carrier phytoconstituents delivery3. Aloe vera in topical and transdermal drug delivery systems4. Biomaterials in inhalation and nasal drug delivery5. Lipid-based cubosomes for modified-release drug delivery6. Cationic nanoparticles for drug delivery targeting the brain7. Advances in biomaterials for targeted brain drug delivery8. Bacterial cellulose composites for drug and protein delivery9. Hydrogels for drug deliverySECTION 3: BIOMATERIALS FOR GENE, VACCINE AND THERAPEUTICS DELIVERY10. Marine-based biopolymers for gene delivery11. Biomaterials RNAi-, mRNA and DNA-based delivery and therapeutics12. Biomimetic nanoparticles as vaccine delivery platforms13. Bacterial cellulose composites for oral vaccine delivery14. Proteins and peptides for therapeutics15. Synthetic polymers for therapeuticsSECTION 4: BIOMATERIALS FOR WOUND AND TISSUE REGENERATION16. Biomaterials in tissue engineering - an introduction17. PLGA microparticles for wound healing18. Hydroxyapatite for bone tissue repair and regeneration19. Alginate biocomposite nanofibers in wound healing and tissue regeneration20. Nanocellulose biocomposites in wound healing applications21. Bacterial cellulose composites for cell delivery in wound healing22. Hydrogels for wound healingSECTION 5: BIOMATERIALS - SAFETY AND REGULATORY CONSIDERATIONS23. Zebrafish larvae models: Biomaterials safety for drug delivery24. Safety, biocompatibility, and preclinical considerations for biomaterials25. Regulatory considerations for biomaterials in medical applications