Metabolic and Bioenergetic Drivers of Neurodegenerative Disease: Treating Neurodegenerative Diseases as Metabolic Diseases

1. Dysregulation of metabolic flexibility: The impact of mTOR on autophagy in neurodegenerative diseasesKenneth Maiese2. Antidiabetic drugs for Alzheimer¿s and Parkinson¿s diseases: Repurposing insulin, metformin and thiazolidinedionesSusana Cardoso and Paula I. Moreira3. Evidence for pathophysiological commonalities between metabolic and neurodegenerative diseasesChristian Hölscher4. Repurposing GLP1 agonists for neurodegenerative diseasesIoanna Markaki, Kristian Winther, Sergiu-Bogdan Catrina and Per Svenningsson5. A role for Sodium Glucose coTransporter 2 inhibitors (SGLT2i) in the treatment of Alzheimer's disease?Russell Esterline, Jan Oscarsson and Jeffrey Burns6. Ketotherapeutics for neurodegenerative diseasesNicholas G. Norwitz, Javier Gilbert Jaramillo, Kieran Clarke and Adrian Soto7. Enhancing mitophagy as a therapeutic approach for neurodegenerative diseasesYahyah Aman, Brent Ryan, Silje Bøen Torsetnes, Anne-Brita Knapskog, Leiv Otto Watne, William A. McEwan and Evandro Fei Fang8. Cellular senescence in aging and age-related disorders: Implications for neurodegenerative diseasesErin O. Wissler Gerdes, Yi Zhu, Bettina M. Weigand, Utkarsh Tripathi, Terence C. Burns, Tamar Tchkonia and James L. Kirkland9. Harnessing neurogenesis in the adult brain-A role in type-2-diabetes mellitus and Alzheimer's diseaseOrly Lazarov, Richard D. Minshall and Marcelo G. Bonini10. Hormesis: A therapeutic strategic approach in the treatment of neurodegenerative diseaseEdward J. Calabrese, Mark P. Mattson, Gaurav Dhawan, Rachna Kapoor, Vittorio Calabrese and James Giordano