Cannabis Use, Neurobiology, Psychology, and Treatment

Preface I. Setting the scene and introductory chapters 1. Metabolomics of the cannabis plantMickel Hiebert-Giesbrecht, Claudia Torres-Calzada and David Scott Wishart 2. The roots of Cannabis sativa: chemical and pharmacological profileL A. Rolim 3. Cannabis related compounds in beverages and foodIlaria Di Marco Pisciottano 4. The impact of prenatal cannabis exposure: an overviewNatalia Kleinhans 5. Cannabis Genotoxicity and Cancer Incidence: Highly Concordant Synthesis of European and USA DatasetsAlbert Stuart Reece and Gary K. Hulse 6. Cannabis Genotoxicity and Cancer Incidence: A Highly Concordant Synthesis of European and USA DatasetsAlbert Stuart Reece and Gary K. Hulse 7. Cannabis, Cognitive impairment and Car Crash risk U.W. Preuss II. Cannabis usage 8. Recreational cannabis use: a French perspective of adverse effectsEmilie Bouquet, Emilie Jouanjus and Maryse Lapeyre-Mestre 9. Acute and chronic impact of cannabis on human cognitionJustin Matheson and Bernard Le Foll 10. Polydrug users, use of cannabidiol (CBD) and abuse potential/Polydrug users, use of cannabinoids and abuse potentialKerri Alexandra Schoedel 11. Cannabis stigmas: a narrative of featuresMatt Reid 12. Alterations of THC and CBD ratios and impact on cognitionErica Zamberletti 13. When cannabis is used for medicinal purposes: a focus on back painR. L. Price III III. Pharmacological and Physiological Aspects 14. Cannabis, cannabinoids and receptor responsesYi Yang, Roya Derwish and Lakshmi P. Kotra 15. Cannabidiol (CBD): abuse potential and withdrawalKenneth W. Sommerville and Beatrice Setnik 16. 4,5- Dihydro-1H-pyrazole/3,4-Diarylpyrazoline class of cannabinoid-1 (CB1R) receptor antagonists and their potential in medicinal applications Malliga R. Iyer IV. Neurobiology of cannabis 17. Neurobiology of cannabisRohit Goyal and Deepak Kumar 18. The kynurenine pathway, neurobiology and cannabis misuse: a new narrativeNuria Morales-Puerto and Esther O'Shea 19. Central nervous system cancers and use of cannabis and related products: an updated narrativeJ. Eduardo Rodriguez Almaraz and Nicholas Butowski 20. Chronic cannabis users: links with glutamate and resting state connectivityS.D. Newman 21. Brain metabolic responses to cannabis use in people with multiple sclerosis: Insights from [18F]-FDG positron emission tomography and functional MRIThorsten Rudroff 22. Genetic Variation and Acute Responses to Cannabis Bernard Le Foll, Zoe Bourgault and Justin Matheson 23. Cell Signaling of the CB1 Cannabinoid Receptor via beta-arrestins, Cannabinoid Receptor Interacting Protein (CRIP1a) and other regulatory proteinsAllyn C. Howlett 24. Cannabis and impact on memory: from in utero to adultsJennifer Willford, Meaghan Hazelet, Mohamad Khalaifa, Natacha DeGenna and Gale A. Richardson 25. Central CB1 receptors and age-related changes: investigating the effects of DELTA-9-tetrahydrocannabinolBrett C. Ginsburg and Hanana AlTfaili 26. Alcohol, cannabis and visual memoryConcepcion Vinader-Caerols V. Neurobiology of cannabinoids 27. The role of Delta-FosB in the plasticity of the cannabinoid systemArturo Venebra-Munoz and Sara Mejía-Chávez 28. Functional profile of synthetic cannabinoid receptor agonists: exploring cannabinoid and non-cannabinoid targets Shivani Sachdev, Marina Santiago and Chris Bladen 29. Linking the G protein-coupled orphan receptor GPR55 to the cannabinoid receptors (CB1 and CB2): a new narrativePaula Morales, Raquel Guerrero-Alba and B.A. Marichal-Cancino 30. Proteomic analysis of cannabinoids in human oligodendrocytesValéria Almeida 31. Cannabinoids and endocannabinoid signaling at the basal forebrain cholinergic systemRafael Rodriguez 32. Cannabidiol (The major non-psychotropic cannabinoid in the cannabis plant) and the PI3K/Akt pathway in the CNSNadja Schroder 33. Effects of cannabidiol and other phytocannabinoids on ion channelsMurat Oz, Keun-Hang Susan Yang, Mohamed Mahgoub, Georg Petroianu and Dietrich Lorke 34.