Cancer Epigenetics, Guns and Triggers: Targeting the Right Player via Nanotechnology Approach is a complete package that provides a comprehensive and thorough understanding of the key players that modulate the various steps of carcinogenesis and malignant progression of the disease and the critical targets to be exploited for developing novel modalities of diagnosis and therapeutics.
Since epigenetic aberrations can be potentially reversed and restored to their normal state through epigenetic therapy, the book also discusses the challenges and the future of the field with the cutting-edge revelations and limitations that this research endeavor can offer, thereby helping the readers to enhance their critical thinking and adopt strategies of therapeutic importance.
- Delivers a detailed and complete journey of how cancer develops, its genetics, as well as other internal and external factors that are contributors of carcinogenesis
- Provides in-depth knowledge on epigenetics and the various epigenetic biomolecules, enzymes, and other signaling pathways that are promising entities for drug discovery and chemotherapeutics
- Presents state-of-the-art information on the next-generation cancer therapies, challenges, and future of the field
Sprache
Verlagsort
Verlagsgruppe
Elsevier Science & Techn.
Dateigröße
ISBN-13
978-0-443-13210-0 (9780443132100)
Schweitzer Klassifikation
SECTION 1 Overview of cancer, internal and external factors associated with cancer1. Overview of cancer: Mechanisms of carcinogenesis2. Tumor metabolism and micronutrients: New insights to target malignant tumors3. The role of one-carbon amino acids in tumor-immune metabolism: From oncogenesis to therapy4. Environmental causes of cancer5. Cancer stem cells-Challenges for cancer therapies6. Carving a therapeutic niche for metastatic cancer: Opportunities and challengesSECTION 2 Epigenetics and its importance in cancer therapies7. An overview of epigenetics and cancer8. Metabolic adaptation and epigenetic modulations: Unraveling tumor plasticity under variable tumor microenvironment9. Involvement of epigenetic modifications in cancer stem cells and chemoresistance10. Cancer biomarkers: Where genetics meets epigenetics11. Epigenetics approach in cancer treatment with focus on lung and breast cancer12. Dietary components as epigenetic modifiers and their roles in cancer preventionSECTION 3 Nanomedicine targeting epigenetic machinery in cancer therapy13. Harnessing plant-derived biosynthetic nanomaterials for epigenetic modulation in cancer therapy14. Nanotechnology-enhanced immunotherapy for cancer15. Nanoparticles in metastatic cancer treatment16. Amine-terminated dendrimers: A novel method for diagnose, control and treatment of cancer17. Nanomedicine and epigenome: Possible health risks, benefits, and future perspectives18. Smart cancer nanomedicine: Challenges and future opportunities
