Peptide and Protein Drug Delivery Using Polysaccharides offers an interdisciplinary discussion of polysaccharides applied in peptide and protein drug delivery. Chapters consider basic biology of different polysaccharides of current interest and their production at pilot and large-scale stages by various techniques including, but not limited to, cell and hairy root cultures. Other sections examine factors affecting polysaccharide absorption, metabolism, and excretion in nascent, encapsulated, or conjugated forms, with unique coverage of vaccine absorption, metabolism, and drug delivery. A final section considers analytical methods for detection in tissue fluids and homogenates. Accessible figures, tables, and graphical abstracts are included throughout to support understanding.
Specific polysaccharides discussed for therapeutic purposes include cellulose, hyaluronic acid, heparin, carageenan, alginic acid, agar and myrrh, acacia, tragacanth, ghatti gum, chitin, chitosan, starch, glycogen and dextran.
- Adopts an interdisciplinary approach across biochemistry, molecular biology, pharmaceutical sciences and drug delivery, and biotechnological perspectives
- Features accessible figures, tables and graphical abstracts across all chapters to support understanding
- Examines various polysaccharides of current interest and aspects affecting their absorption, metabolism, excretion and detection
Sprache
Verlagsort
Verlagsgruppe
Elsevier Science & Techn.
Dateigröße
ISBN-13
978-0-443-18926-5 (9780443189265)
Schweitzer Klassifikation
1. Peptide and Protein in Therapeutics2. Hairy root culture: a reliable bioreactor from transgenic plants3. Strategies for the ameliorated production of pharmaceutically important glycosides via plant cell culture4. Peptide and protein delivery through cellulose, hyaluronic acid and Heparin5. Peptide and protein delivery through Carageenan, Alginic acid, Agar and Myrrh6. Peptide and protein delivery through acacia, tragacanth, and ghatti gum7. Peptide and protein delivery through Chitin, chitosan and Starch8. Peptide and protein delivery through Glycogen and Dextran9. Peptide and protein in vaccine delivery10. Analytical methods in detection of proteins and peptides in tissue fluids and homogenates11. Factors affecting Peptide and protein absorption, metabolism and excretion