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This book reviews the potential of unconventional production organisms in biotechnology, emphasizing their role in enhancing bioprocess efficiency and sustainability. By focusing on a diverse range of microorganisms, such as the archaea Methanothermobacter thermautotrophicus and the fast-growing bacterium Vibrio natriegens, the book highlights the opportunities and needs for integrating these organisms into biotechnological applications.
The chapters cover topics such as the utilization of alternative substrates like CO2 and methane, adaptation to unusual process conditions, and the exploitation of microbial diversity for enhanced biofilm growth and electron transport systems. Each chapter begins with an overview of the microbiological and biochemical characteristics of the organisms, followed by discussions on their biotechnological applications. Readers will also find expert analysis of the current challenges and future trends in the application of these organisms, making the book a must-read for anyone interested in advancing bioprocess technologies.
Given its breadth, this book is an invaluable resource for researchers, scholars, and practitioners in biotechnology and related fields. It provides cutting-edge insights into the development of processes based on alternative organisms, and their role in shaping the future of biotechnology.
Dirk Holtmann is a leading expert in electrobiotechnology and industrial biotechnology, with over two decades of experience in advancing sustainable bioprocess technologies. He studied Chemical Engineering and Biotechnology and earned his Ph.D. at the University of Magdeburg, Germany, focusing on electrochemical monitoring of microbial activity for wastewater treatment. Prof. Holtmann has held key research and leadership roles, including Group Leader for Industrial Biotechnology at DECHEMA Research Institute in Frankfurt am Main (2019-2023). Since 2023, he has been W3-Professor for Electrobiotechnology at the Karlsruhe Institute of Technology (KIT), Germany. His research emphasizes microbial electrochemical systems, process intensification, and sustainable bioprocessing.
Unconventional Production Organisms in Biotechnology - Opportunities and Needs.- Methanothermobacter thermautotrophicus and alternative methanogens - archaea-based production.- Cupriavidus necator - a "knallgas" bacterium.- Vibrio natriegens - application of a fast-growing halotolerant bacterium.- Shewanella oneidensis - biotechnological application of a metal-reducing bacteria.- Pseudomonas taiwanensis and Pseudomonas putida - solvent tolerant bacteria.- Synechocystis sp. PCC6803 and Synechococcus UTEX - biotechnological applications of cyanobacteria.- Cable-bacteria and their biotechnological application.- Parageobacillus thermoglucosidasius - application of a carboxydotrophic bacteria.- Dictyostelium discoideum - Amoebae as potential host organisms for complex substances.- Bioproduction with the mixotroph algae Euglena gracilis.
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