Kratom: History, Science and Therapeutic Potential is the first book to address the unregulated, widespread availability of kratom, with its weak opioid and stimulant effects, coupled with limited awareness of it by healthcare professionals. Kratom has great therapeutic utility and medicinal potential, but more study, caution, and possible regulation is needed. It discusses geographical sourcing, historical uses, current worldwide uses, and potential for treatment of other medical conditions. Most exciting for healthcare professionals will be the implications of this substance's potential for treatment of diseases like depression, ADHD, PTSD, and substance-use disorder, particularly opioid use disorder (OUD).Moreover, kratom and its active alkaloid mitragynine are getting remarkable attention at federal and local governments as more than eight million Americans consume this product annually. Yet, the paucity of information for researchers and clinicians is troublesome.
- Provides healthcare scientists and researchers with awareness on kratom and its emerging trend as a therapy for medical use for many medical applications
- Presents cutting-edge science for healthcare providers of a substance that will soon be as topical as medical marijuana
- Offers scientists and others information to help those involved in emerging decisions regarding legal status and regulations
Sprache
Verlagsort
Dateigröße
ISBN-13
978-0-443-27413-8 (9780443274138)
Schweitzer Klassifikation
Section 1: Background1. Botany, geographical distribution, and phytochemistry of Mitragyna speciosa (Korth.) and related speciesSatya Swathi Nadakuduti, Mengzi Zhang, Larissa C. Laforest and Brian Pearson2. The scientific evolution of kratom: a historical overviewThiruventhan Karunakaran, Yathindra Marimuthu, Balasingam Vicknasingam and Marek C. Chawarski3. Recent patterns and reasons for useMarc T. Swogger, Kirsten E. Smith, Tianna Torrice and Oliver GrundmannSection 2: Basic science4. Chemistry and metabolites: ADMEManoj Gundeti, Christopher R. Mccurdy and Abhisheak SharmaSection 3: Current therapeutic uses5. Kratom-related physical dependence and addictionKirsten E. Smith, Darshan Singh and Oliver Grundmann6. Current therapeutic usesNorsyifa Harun, Siti Rafidah Yusof and Farah Wahida SuhaimiSection 4: Pharmaceutical drug development of kratom-derived products7. Regulation and policy regarding kratom-derived dietary supplements and direct-to-consumer salesRobert Durkin, Oliver Grundmann and Kirsten E. Smith8. Patentability and exclusivity of kratom based natural productsRobert ParadisoSection 5: Concerns9. Kratom drug-drug (and other) interactionsRobert B. Raffa and Jeanette Mathews10. Susceptible populationsRobert B. Raffa and Jeanette MathewsSection 6: Commentaries/Perspectives11. Kratom purity and quality control issues: an in-depth analysisFrank Breve12. Kratom entrepreneurship | exploiting the commercial potential of kratom and its active alkaloidsChad E. Beyer13. Equity investment into kratom, mitragynine, and related productsZachariah Mcintosh-Pearce14. Medical marijuana as a template for understanding kratomSoren Shade
