The Functions, Disease-Related Dysfunctions, and Therapeutic Targeting of Neuronal Mitochondria

Section I: Mitochondrial Structure and Ion Channels
Chapter 1: Mitochondrial Permeability Transition: Look from a Different Angle
N. Brustovetsky
Chapter 2: The mitochondrial permeability transition pore, the c-subunit of the F1FO ATP synthase, cellular development and synaptic efficiency
E.A. Jonas, G.A. Porter, Jr., G. Beutner, N. Mnatsakanyan and K.A. Alavian
Chapter 3: Mitochondrial channels in neurodegeneration
P.M. Peixoto, K.W. Kinnally and Evgeny Pavlov
Chapter 4: Mitochondrial Ca¯2+ Transport in the Control of Neuronal Functions: Molecular and Cellular Mechanisms
Y.M. Usachev
Section II: Control of Mitochondrial Signaling Networks
Chapter 5: AMP-activated Protein Kinase (AMPK) as a Cellular Energy Sensor and Therapeutic Target for Neuroprotection
P. Weisova, S. Pfeiffer and J.H.M. Prehn
Chapter 6: HDAC6: a molecule with multiple functions in neurodegenerative diseases
Y. Yan and R. Jiao
Chapter 7: Neuronal Mitochondrial Transport
A.L. Knight, Y. Chen, T. Sun and Z.H. Sheng
Chapter 8: Mitochondria in Control of Hypothalamic Metabolic Circuits
C.M. Nasrallah and T.L. Horvath
Chapter 9: Mitochondria Anchored at the Synapse
G.A. Spirou, D. Jackson and G.A. Perkins
Section III: Defective Mitochondrial Dynamics and Mitophagy
Chapter 10: Neuronal mitochondria are different: relevance to neurodegenerative disease
S.B. Berman and J.M. Hardwick
Chapter 11: PINK1 as a Sensor for Mitochondrial Function: Dual Roles
E.K. Steer, M.K. Dail and C.T. Chu
Chapter 12: A get-together to tear it apart: the mitochondrion meets the cellular turnover machinery
G.L. McLelland and E.A. Fon
Chapter 13: Mitochondrial involvement in neurodegenerative dementia
L. Bonanni, V. Frazzini, A. Thomas and M. Onofrj
Section IV: Mitochondria-Targeted Therapeutics and Model Systems
Chapter 14: Neuronal Mitochondria as a Target for the Discovery and Development of New Therapeutics
V.K. Gribkoff
Chapter 15: Mitochondria as a Therapeutic Target for Alzheimer's disease
C.H.L. Hung, S.S.Y. Chung, S.M.Y. Lee and R.C.C. Chang
Chapter 16: Mitochondria in Parkinson Disease
G. Arena and E.M. Valente
Chapter 17: Therapeutic Targeting of Neuronal Mitochondria in Brain Injury
H.M. Yonutas, E.D. Hall and P.G. Sullivan
Chapter 18: The use of fibroblasts from patients with inherited mitochondrial disorders for pathomechanistic studies and evaluation of therapies
D. Soiferman and A. Saada