Liposome Technology

VOLUME I. Formation and Properties of Fatty Acid Vesicles (Liposomes). Formation and Physicochemical Properties of Lipid Vesicles (Liposomes) by the Coacervation Method. Preparation of Liposomes and Oily Formulations by Freeze-Drying Monophase Solutions. Formation of Large Unilamellar Vesicles by Extrusion. Preparation of Liposomes for Pulmonary Delivery Using Medical Nebulizers. Immunopotentiating Reconstituted Influenza Virosomes. Lipoplexes in Gene Therapy under the Considerations of Scaling Up, Stability Issues and Pharmaceutical Requirements. Synthesis and Advantages of Acid-Labile Formulations for Lipoplexes. Bioresponsive Lipids and Their Use for Macromolecular Delivery. Polymeric Vesicles Based on Hydrophilic Polymers Bearing Hydrophobic Pendant Groups. Mixed Vesicles and Mixed Micelles: Formation, Thermodynamic Stability and Pharmaceutical Aspects. Vesicular Phospholipid Gels. Stabilization of Liposomes by Freeze-Drying: Lessons from Nature. Hydrolysis of Phospholipids in Liposomes and Stability Indicating Analytical Techniques. Process Development and Quality Control of Injectable Liposomal Therapeutics. VOLUME II. Amphipathic Weak Base Loading into Preformed Liposomes Having a Transmembrane Ammonium Ion Gradient: From the Bench to Approved DOXIL. Encapsulation of Drugs within Liposomes by pH Gradient Techniques. Incorporation of Lipophilic Antitumor and Antiviral Drugs into the Lipid Bilayer of Small Unilamellar Liposomes. Liposome-Encapsulated Hemoglobin as an Artificial Oxygen Carrier. An Original Lipid Complex System for Amphotericin B. Coupling of Peptides to the Surface of Liposomes: Application to Liposome-Based Synthetic Vaccines. Encapsulation of Nucleic Acid-Based Therapeutics. Intraliposomal Trapping Agents for Improving In Vivo Liposomal Drug Formulation Stability. Radiolabeling of Liposomes for Scintigraphic Imaging. Liposomal Bisphophonates for the Treatment of Restenosis. Development of a Liposomal Vaccination Syst