T. cruzi Infection

Computer-Aided Discovery of Drugs Against Chagas Disease.- Chromatin Interaction Maps of Trypanosoma cruzi.- GCanner, a Genome-Wide GC Composition Tool for the Unbiased Assessment of Trypanosoma cruzi Genomic Compartments.- An Algorithm for Annotation of Trypanosoma cruzi MASP Sequences Employing Hidden Markov Models.- Cloning-Free Genome Editing by CRISPR/T7RNAP/Cas9 in Trypanosoma cruzi.- Typification of Trypanosomatids Using Amplicon-Based Sequencing.- Deep Amplicon Sequencing of Minicircle Hypervariable Regions (mHVRs) for High-Resolution and Sensitive Trypanosoma cruzi Genotyping.- Identification of Trypanosoma cruzi Discrete Typing Units by Multiplex Real-Time PCR.- Real-Time PCR Assays for Quantification of Trypanosoma cruzi in Food Samples: A Tool for Surveillance of Oral Chagas Disease Outbreaks.- Ultra-Rapid DNA Extraction Coupled with Loop-Mediated Isothermal Amplification for Point-of-Care Detection of Trypanosoma cruzi Infection in Heparinized Blood and Dried Blood Spots.- Quantitative Real-Time PCR for Trypanosoma cruzi Infection Diagnosis and Treatment Response Monitoring of Patients with Chagas Disease.- Standardization of Serodiagnostic Methods for Trypanosoma cruzi.- Software and Tools to Analyze High-Density Peptide Array Data for the Chagas Antigen and Epitope Atlas.- Conjugation of Saccharidic Synthetic Antigens with Carrier Proteins by the Squaric Acid Method: Application as Biomarkers for Treatment Evaluation in Chagas Disease.- Identifying Trypanosoma cruzi Proteins Targeted by Chagas Disease Patient Antibodies Using Yeast Surface Display.- Profiling T-Cell Receptor and Immunoglobulin Repertoires through RNA-Sequencing to Understand Host Response to Trypanosoma cruzi Infection.- The Use of B-Cell Tetramers for the Study of Trypanosoma cruzi-Specific B-Cell Responses.- ELISPOT-Based Measurement of Antibody Secreting Cells and Memory B-Cells Specific to Trypanosoma cruzi in Chronically Infected Subjects.- Host-Derived Molecules as Novel Chagas Disease Biomarkers: Hypercoagulability Markers and Extracellular Vesicles.- Advanced Identification of Trypanosoma cruzi-Specific CD4+ and CD8+ T-Cells in Chronic Chagas Disease Patients Using Activation-Induced Marker (AIM) Assay.- Assessing the Metabolic Profile of CD4+ and CD8+ T-Lymphocytes in Chronic Chagas Disease Patients Using SCENITH.- A Single Cell Methodology for Energy Metabolism Analysis in Parasitic Protozoa.- Determining Histone Post-Translational Modifications along the Cell Cycle in Trypanosoma cruzi by Flow Cytometry.- Ultrastructure Expansion Microscopy for the Analysis of Trypanosoma cruzi Infection.- An In Vitro 3D Collagen-I Model for Studying Trypanosoma cruzi Trypomastigote Motility.- A Rapid Method for Purifying Intact Trypanosoma cruzi Amastigotes from Host Cells, In Vitro and In Vivo, for Downstream 'Omic Analysis.- Insights into the Procedures and Interpretation of Autophagy in Trypanosoma cruzi.- Animal Models for Studying Trypanosoma cruzi Congenital Transmission and Associated Pathogenesis: Special Emphasis on Guinea Pig Model.