Primer on Multiple Sclerosis

Part 1: Historical Background Chapter 1: The History of Multiple Sclerosis: From the Age of Description to the Age of Therapy T. Jock Murray Part 2: Basic Science Chapter 2: Genetics and Epidemiology in Multiple Sclerosis Gabriele C. DeLuca, Richard L. Yates and A. Dessa Sadovnick Chapter 3: Neurophysiology of Multiple Sclerosis Jefferson C. Slimp Chapter 4: Immunology of Multiple Sclerosis Laura Piccio and Anne H. Cross Chapter 5: Taking a Microscopic Look at Multiple Sclerosis Yong Guo and Claudia F. Lucchinetti Part 3: Diagnosis and Prognosis Chapter 6: Diagnosis of Multiple Sclerosis Loren A. Rolak Chapter 7: Neuroimaging in Multiple Sclerosis Megan Esch & Nancy L. Sicotte Chapter 8: Cerebrospinal Fluid Profile Supporting a Clinical Definite Multiple Sclerosis Diagnosis Mark Freedman and Mohammed Abdoli Chapter 9: Evoked Potentials Marc R. Nuwer Chapter 10: Temporal and Clinical Course of Multiple Sclerosis Erica Grazioli, Cornelia Mihai, and Bianca Weinstock-Guttman Chapter 11: Outcome Measures in Multiple Sclerosis Robert M. Herndon Part 4: Clinical Manifestations Chapter 12: Neuro-Ophthalmologic Manifestations of Multiple Sclerosis Shin C. Beh, Elliot M. Frohman, and Teresa Frohman Chapter 13: Cerebellar and Brainstem Dysfunction in Multiple Sclerosis Angeli S. Mayadev and George H. Kraft Chapter 14: Disorders of Mobility in Multiple Sclerosis Scott Campea and Jodie K. Haselkorn Chapter 15: Management of Urinary and Bowel Dysfunction in Patients with Multiple Sclerosis Ja-Hong Kim and Judy M. Choi Chapter 16: Assessment and Treatment of Sexual Dysfunction in Multiple Sclerosis Frederick W. Foley Chapter 17: Gender and Reproductive Issues in Multiple Sclerosis Rhonda Voskuhl and Barbara S. Giesser Chapter 18: Cognitive Impairment and Mood Disturbances Nicholas G. LaRocca Chapter 19: Multiple Sclerosis and Pain Norman S. Namerow Chapter 20: Fatigue in Multiple Sclerosis Vikram Bhise, Leigh Charvet, and Lauren Krupp Chapter 21: Sleep Disorders in Multiple Sclerosis Tiffany J. Braley and Alon Y. Avidan Chapter 22: Pediatric Multiple Sclerosis J.M. Tillema, J. Graves, L.A. Benson, G.S. Aaen, A. Belman, J. Parrish, B. Weinstock-Guttman, L. Krupp, T. Chitnis, and E. Waubant, Part 5: Therapeutics Chapter 23: Neuromyelitis Optica Spectrum Disorders Dean M. Wingerchuk Chapter 24: Multiple Sclerosis Nursing Kirstin Nygren and Gail Hartley Chapter 25: Immunomodulatory Agents for Relapsing-Remitting Multiple Sclerosis Jessica F. Robb and Lawrence M. Samkoff Chapter 26: Immunosuppressive and Novel Therapies Barbara S. Giesser Chapter 27: Complementary and Alternative Medicine in Multiple Sclerosis Allen C. Bowling Part 6: Psychosocial Issues Chapter 28: Living with Multiple Sclerosis: The Psychosocial Challenges for Patients and Their Families Rosalind C. Kalb Chapter 29: Employment and Career Development Considerations Steven W. Nissen and Phillip D. Rumrill, Jr. Chapter 30: Legal Planning Issues Laura D. Cooper, Esq. Part 7: Research Chapter 31: Issues in the Design and Interpretation of Multiple Sclerosis Clinical Trials Stephen Krieger, Ilana Katz Sand, Svenja Oynhausen, and Aaron Miller Chapter 32: Basic Science in Multiple Sclerosis: Progress and Promise Wendy Gilmore and Leslie P. Weiner