Epigenetics in Organ Specific Disorders

1. Introduction to epigenetic mechanisms2. Epigenetic signatures that maintain stemness in pluripotent and mesenchymal stem cells3. Cell-cell and Cell-matrix interactions mediated by histone deacetylases4. Enhanced cell proliferation and altered gene expression due to actions of DNA methyltransferases5. Histone deacetylases and regulation of gene expression during cell proliferation6. Epigenetic mediators that promote cytoskeletal reorganization and cell migration7. Inhibition of cellular apoptosis and senescence by unique epigenetic proteins8. Epigenetic mechanisms involved in the regulation of necrosis and pyknosis9. Epigenetic control over cell division in pathological conditions10. Regulated expression of tumor suppressor proteins by DNA methyltransferases during cell cycle progression11. Role of histone deacetylases in regulating cell cycle progression12. Phenotype switch and cell differentiation in immune and non-immune cells regulated by different epigenetic mediators13. Epigenetic pathways that promote cellular autophagy14. Epigenetic inducers of Cell growth and survival15. Microbial compounds as potential inducers of epigenetic mechanisms during infections16. Current epigenetic drugs and their target proteins with potential use in disease treatment17. Prospects of epigenetic drugs in combination therapy