Navigating Endophytic Research for Next-Generation Therapeutics explores the evolving field of endophytic fungal research and applications in combating diseases, addressing environmental challenges, and in shaping the future of therapeutics. The book starts off with a discussion on the biodiversity and biogeography of endophytic fungal communities and describes the bioprospecting of endophytes for drug discovery. In addition, it covers the therapeutic application of endophytic fungi to treat and manage specific diseases and investigates the innovative use of technologies such as genome editing, genetic engineering for enhanced bioactivity, multi-omics-based exploration, and the use of big data and machine learning in endophytic drug discovery.Featuring contributions from experts across fields like mycology, pharmacology, biotechnology, and environment science, this comprehensive, practical, and insightful resource guides those engaged in endophytic fungal research and its transformative potential in next-generation therapeutics.
- Explores diverse research techniques for isolating, culturing, and characterizing endophytic fungi
- Demonstrates how endophytic fungi have been successfully utilized in drug discovery and therapeutic applications
- Recognizes the importance of responsible research practices and ethical considerations in bioprospecting and drug development
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978-0-443-31485-8 (9780443314858)
Schweitzer Klassifikation
1. Diversity and Biogeography of Endophytic Fungal Communities2. Bioprospecting Ethnopharmacological Plants for Endophytic Fungal Drug Discovery3. Biological Diversity Hotspots: Exploring Endophytic Fungi in Unique Ecosystems4. Pharmaceutical Applications of Endophytic Fungi: Current Successes and Future Prospects5. Endophytic Fungi in Anti-cancer Drug Development: Targeting Tumor Microenvironment6. Neuropharmacology of Endophytic fungal Bioactives: Promising Leads for Brain Disorders7. Antimicrobial Potential of Endophytic Fungal Compounds: Fighting Drug Resistance8. Immunomodulatory Properties of Endophytic Fungi: Implications for Therapeutics9. Antioxidant and Anti-inflammatory Endophytic Fungal Compounds for Chronic Diseases10. Endophytic Fungi and Metabolic Disorders: From Diabetes to Obesity11. Endophytic Fungi as Sources of Cardiovascular Drug Leads12. Commercialization of Endophytic Fungal-Derived Therapeutics: Opportunities and Challenges13. Clinical Trials and Commercialization of Endophytic Fungal-Derived Therapeutics14. Endophytic Fungi and Multi-omics Integration: Data-Driven Drug Discovery15. Endophytic Fungi in Aquatic Environments: Exploring Novel Drug Resources16. Endophytic Fungi and Age-Related Diseases: Potential for Geriatric Therapeutics17. Endophytic Fungi and Natural Insecticides: Eco-friendly Alternatives for Pest Control18. Endophytic Fungal-Derived Antivirals: Expanding the Armamentarium Against Emerging Pathogens19. Bioprospecting Extremophiles: Endophytic Fungi from Extreme Environments20. Nanotechnology and Endophytic Fungi: Advancements in Drug Delivery and Targeting21. Bioinformatics and Omics Tools in Endophytic Fungal Research22. Genetic Engineering of Endophytic Fungi for Enhanced Bioactivity23. Metabolomics and Natural Product Profiling of Endophytic Fungi24. Big Data and Machine Learning in Endophytic Drug Discovery: Accelerating Innovations25. Endophytic Fungi from Marine Environment and their Bio-Actives, Genome Editing, Endophytic Fungi for Biotransformation
