Posttraumatic Stress Disorder

List of contributors, vii
Introduction, xi
Section I: Preclinical sciences of stress
1 Posttraumatic stress disorder: from neurobiology to clinical presentation 3
Arieh Y. Shalev & J. Douglas Bremner
2 The epidemiology of posttraumatic stress disorder in children and adolescents: a critical review 27
Leah A. McGuire
3 Early life stress and development: preclinical science 61
Dora B. Guzman, Brittany Howell & Mar Sanchez
4 Amygdala contributions to fear and safety conditioning: insights into PTSD from an animal model across development 81
Christopher Cain & Regina Sullivan
5 Preclinical evidence for benzodiazepine receptor involvement in the pathophysiology of PTSD, comorbid substance abuse, and alcoholism 105
Robert Drugan, Nathaniel P. Stafford & Timothy A. Warner
6 Psychosocial predator stress model of PTSD based on clinically relevant risk factors for trauma-induced psychopathology 125
Phillip R. Zoladz & David Diamond
7 Coping with stress in wild birds - the evolutionary foundations of stress responses 145
Molly J. Dickens & Michael Romero
8 Stress, fear, and memory in healthy individuals 159
Christian J. Merz, Bernet M. Elzinga & Lars Schwabe
Section II: Neurobiology of PTSD
9 Neurotransmitter, neurohormonal, and neuropeptidal function in stress and PTSD 181
J. Douglas Bremner & Brad Pearce
10 Genomics of PTSD 233
Anthony S. Zannas, Elisabeth Binder & Divya Mehta
11 Cortisol and the Hypothalamic-Pituitary-Adrenal Axis in PTSD 265
Amy Lehrner, Nicolaos Daskalakis & Rachel Yehuda
12 Neuroimaging of PTSD 291
Carolina Campanella & J. Douglas Bremner
Section III: PTSD and co-occuring conditions
13 PTSD and mild traumatic brain injury 321
J. Douglas Bremner
14 Stress-related psychopathology and pain 345
Sarah C. Reitz, Karl-Juergen Bär & Christian Schmahl
15 Stress and health 361
Viola Vaccarino, Emeran Mayer & J. Douglas Bremner
Section IV: PTSD: from neurobiology to treatment
16 Pharmacotherapy for PTSD: effects on PTSD symptoms and the brain 389
Lori Davis, Mark Hamner & J. Douglas Bremner
17 Effects of psychotherapy for psychological trauma on PTSD symptoms and the brain 413
J. Douglas Bremner & Carolina Campanella
Index 421