Plant-Based Drug Discovery: Unveiling Molecular Targets for Metabolic Conditions provides an in-depth examination of the molecular mechanisms of phytochemicals and their potential in treating metabolic diseases. This comprehensive guide begins with an introduction to the prevalence and impact of metabolic disorders, emphasizing the significant role of phytochemicals in their management. The book delves into scientific concepts and research findings, offering valuable insights for researchers and healthcare professionals in the fields of molecular biology, biochemistry, pharmacology, and biotechnology. Chapters cover various crucial topics such as oxidative stress, epigenetic mechanisms, and mitophagy.In addition, they explore the targeting of molecular chaperones and the molecular targets of plant nutraceuticals for treating obesity, cardiovascular disease, and type 2 diabetes. The book also addresses technological advances, including AI and nanotechnology, highlighting opportunities and challenges in improving the use of plant molecules for metabolic disorder treatments. It serves as an essential resource for those engaged in drug discovery and related areas.
- Considers the therapeutic application of phytochemicals for the treatment of metabolic diseases, including cardiovascular disease, obesity, and type 2 diabetes
- Explores phytochemicals at the molecular level, covering signaling pathways of oxidative stress, mitophagy, inflammasomes, molecular chaperones, receptors, and how these mechanisms can be used to treat diseases
- Discusses the use of artificial intelligence and high-throughput omics technologies in plant-based drug discovery
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ISBN-13
978-0-443-31699-9 (9780443316999)
Schweitzer Klassifikation
Section 1: Introduction1. Overview of human metabolic diseases associated with lifestyleSection 2: Phytochemicals and molecular targets2. Significance of phytochemicals in metabolic disorders3. Molecular connection of oxidative stress and metabolic syndrome: Therapeutic role of phytocomponents4. Epigenetic mechanisms of phytochemicals in cure of metabolic diseases5. Plant-derived bioactive peptides for treatment of metabolic disorders6. Efficiency of phytochemicals to cure metabolic diseases by targeting mitophagy7. Phytochemicals as promising therapeutic approaches for inflammasome-related metabolic diseases8. Regulatory impact of phytochemicals on metabolic diseases by targeting Nrf2-ARE signaling mechanism9. Targeting molecular chaperones with phytochemicals for drug discovery in metabolic ailments10. Molecular targets of plant nutraceuticals against obesity11. Molecular insight to cure cardiovascular diseases through plants compounds12. Mechanistic insights of important medicinal plant compounds in managing type 2 diabetes mellitusSection 3: Nanotechnology methods13. Attenuation of hyperlipidemia by medicinal plants with nanotechnological methodsSection 4: Clinical study14. Clinical evidences of phytochemicals in cure of metabolic diseasesSection 5: Technologies and challenges for plant-based drug discovery15. Artificial intelligence in plant-based drug discovery against metabolic disorders16. Integration of high-throughput omics technologies in discovery of phytodrugs to treat metabolic diseases17. Multi-targets drug design for screening of phytochemicals to cure of metabolic disorders18. New opportunities and challenges for improving the druggability of plant product against metabolic disorders
