Placebo Effects in Neurology delves into the intriguing phenomenon of placebos and their profound impact on neurological disorders. This book explores how placebo effects, occurring both in clinical trials and real-world practice, influence therapeutic outcomes, doctor-patient relationships, and symptom perception. The content provides insights into psychobiological mechanisms and specific conditions such as Parkinson's disease and migraine while addressing ethical and methodological concerns. With discussions on both deceptive and open-label placebos, the book invites readers to reconsider the potential of this underappreciated tool in neurology, offering a bridge between scientific research and practical application in the treatment of various conditions.Beyond its focus on placebo mechanisms, the book examines their role in alleviating symptoms of neuropathic pain, peripheral neuropathies, fatigue, and neuropsychiatric disorders like depression and anxiety. It also presents a methodological lens on how placebos are used to validate treatments in trials while debating their ethical implications. By weaving together science, ethics, and practical insights, Placebo Effects in Neurology stands out as a compelling resource for clinicians, researchers, and anyone interested in the nuanced intersection of psychology and neurology.
- Reviews placebo effects for individual neurological and psychiatric disorders
- Covers benefits in therapeutic outcomes, symptom perception, and doctor-patient relationships
- Discusses the psychobiological mechanisms of how placebos work
- Considers minimizing placebo and nocebo effects in clinical trials
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ISBN-13
978-0-443-29885-1 (9780443298851)
Schweitzer Klassifikation
Section I. GENERAL CONSIDERATIONS1. A brief history of placebo2. Placebo effects and emotion regulation: Conceptual and neural similarities and differences3. Understanding the psychology of the nocebo effect4. Open-label nondeceptive placebos5. Social aspects6. Age and gender7. Conditioned Immune Responses and the neural-immune connection in animals and humans8. The Role of Mindsets in Placebo Effects and Healthcare9. The PlacebomeSection II. SPECIFIC NEUROLOGIC CONDITIONS10. Pain11. The motor system and motor disorders12. Peripheral neuropathies13. Placebo and Nocebo Effects in Headaches14. Placebo Effects in Mental Disorders15. Miscellaneous neurological conditions with a few or no available data16. Hypoxia17. The Placebo Effect in Psychotherapy18. Interventional procedures and physical therapies19. The COVID-19 Pandemic: A Special Case of Placebo and Nocebo EffectsSection III. METHODOLOGICAL AND ETHICAL ISSUES20. Minimizing placebo effects in clinical trials21. Ethical considerations with using placebo treatments and effects in clinical practice22. Placebo and the doctor-patient interaction and communication
