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This book provides a state-of-the-art overview of the pathogenesis, diagnosis, and treatment of a range of inflammatory, autoimmune, and idiopathic disorders. The opening section covers clinical tools with a particular focus on the role of electromyography and MRI imaging. The second section then presents the differential diagnosis of acquired myopathies based on clinical, electrophysiological, muscle biopsy, and serological criteria, discussing in detail relevant clinical conditions such as including myasthenia gravis, polymyositis, and statin myopathies. The third section examines acute and chronic immune-mediated neuropathies, multifocal motor neuropathies, amyotrophic lateral sclerosis, paraneoplastic diseases, and diabetic polyneuropathy, offering clear guidance on available treatments and descriptions of the latest advances in immunotheraphy, drug therapy, and physiotherapy. This clinically oriented book also includes numerous illustrative figures and contributions by international authors from leading centers.
Corrado Angelini has been a Professor of Neurology and Director of the Neuromuscular Center at the Fondazione Ospedale San Camillo IRCCS in Venice since 2010. After completing his MD at the University of Padua and specializing in neurology, Dr. Angelini studied and worked for more than 4 years in the United States (at the Mayo Clinic in Minnesota, Boston, Colorado, and UCLA in Los Angeles, California) before returning to Italy to take up his position at the University of Padua. Dr. Angelini is an associate member and FAAN of the American Academy of Neurology and has been a member of the EAN Muscle and Neuromuscular Junction Committee since 2015. He has received several honors during his career and is the author of numerous articles in international, peer-reviewed journals. Dr. Angelini is a member of the advisory board of Neurology and Neurological Sciences, Acta Myologica and Neuromuscular Disorders and is a Springer author.
Part I Diagnostic Tools.- Autoantibodies in neuromuscular Disorders.- Electromyography.- Imaging of the Muscle.- Peripheral of the Muscle.- Magnetic Resonance Imaging of the Peripheral Nerve.- Part II Clinical Myology Entities.- The Spectrum of Inflammatory Myopathies: Dermatomyositis, Polymyositis and Inclusion-Body.- Necrotizing Autoimmune myopathy.- Statin Myopathy.- Myasthenia Gravis.- Endocrinological Myopathies.- Vitamin D Deficiency in Muscle.- Intensive Care Unit-Acquired Weakness.- Experimental pharmacological interventions.- Part III Neurogenic Disorders.- Idiopathic Chronic Immune-Mediated Neuropathies: Chronic Inflammatory Demyelinating Polyradiculoneuropathy.- Immune Neuropathies.- Amyotrophic Lateral Sclerosis: Epidemiology and Risk.- Paraneoplastic Diseases of the Peripheral Nervous System.- Diabetic Neuropathy.- Infectious Neuropathies.- Toxic neuropathies.
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