Neural Transplantation for Huntington's Disease

This text is a comprehensive review of research into animal models and humans with HD from neurochemical, neuroanatomical and behavioural perspectives. It focuses on neural transplantation studies in rodent and primate models of HD. Studies demonstrating that foetal brain tissue transplants can reverse the neurodegenerative and behavioural pathology of HD animal models are presented. In addition, the final section discusses recent clinical studies on the advantages, future directions and ethical considerations of cell transplantation for HD.