This is a survey of isotopes with particular reference to the fields of analytical chemistry, organic chemistry, medicinal chemistry and radiochemistry. The work is aimed at graduate and senior undergraduate level. In 1981 the first symposium on Isotopes: Essential Chemistry and Applicants was held, and together, the two volumes cover the synthesis of a wide range of isotopically labelled compounds, the analytical methods used and my other important applications. The emphasis in this volume is on short-lived radioisotopes, other analytical methods, particularly radiochromatography and autoradiography and developments in existing methods, particularly nuclear magnetic resonance spectroscopy since 1979. The industrial uses of radioisotopes are emphasized as also are the applications of radiolabelled compounds in molecular biology; applications of compounds, mainly labelled with stable isotopes, in medicinal chemistry are covered. The uses of radiopharmaceuticals for diagnostic purposes as well as positron emission tomography (PET) investigations are the subject of a separate chapter.
Auflage
Sprache
Verlagsort
Zielgruppe
Für höhere Schule und Studium
Editions-Typ
Illustrationen
ISBN-13
978-0-85186-746-5 (9780851867465)
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Schweitzer Klassifikation
Organic synthesis with short-lived positron-emitting radioisotopes, V.W.Pike; radioiodination techniques, D.Silver; the readiochromatography of labelled compounds, W.J.S.Lockley; modern spectrometric methods for the analysis of labelled compounds, F.M.Kaspersen et al; localization and quantittion of radioactivity in solid specimens using autoradiography, M.A.Williams; isotope shifts in NMR spectroscopy - measurement and applications, D.B.Davies et al; the use of stable isotopes in medicinal chemistry, D.Halliday and G.N.Thompson; radiopharmaceuticals, K.Kristensen; isotopes in molecular biology, PLS.G.Goldfarb; industrial applications of radioisotopes, D.J.Lester.
