Contributors Preface Foreword A Selected Glossary of Abbreviations Part One: CRITICAL CARE INTEGRATION SECTION I: INTRODUCTION TO THE PRACTICE OF PEDIATRIC CRITICAL CARE Chapter 1 The History of Pediatric Intensive Care Around the World Chapter 2 Pediatric Intensive Care: A Global Perspective Chapter 3 Impact of Pediatric Critical Care on the Family,Community, and Society SECTION II PROFESSIONALISM, LEADERSHIP, AND SYSTEMS-BASED PRACTICE Chapter 4 Professionalism, Simulation Training, and Leadership in Pediatric Critical Care Chapter 5 Physical Design and Personnel Organization of the PICU Chapter 6 Practice Management: The Business of Pediatric Critical Care Chapter 7 Research Design and Statistical Analysis Chapter 8 Evidence-based Medicine Chapter 9 Severity-of-Illness Scoring Systems Chapter 10 Quality Improvement, Patient Safety, and Medical Error Chapter 11 Information Technology in the PICU SECTION III ETHICAL AND COMPASSIONATE CARE OF THE CRITICALLY ILL CHILD Chapter 12 Pain and Sedation Management in the Critically Ill Child Chapter 13 Rehabilitation of Children with Critical Illness Chapter 14 Ethics SECTION IV BASIC CONCEPTS OF PEDIATRIC CRITICAL CARE Chapter 16 Genomic Medicine Chapter 17 Innate Immunity and Inflammation Chapter 18 Cellular Adaptations to Stress PART TWO EMERGENCY CARE AND ACUTE MANAGEMENT SECTION I INITIAL STABILIZATION Chapter 22 Airway Management Chapter 23 Cardiopulmonary Resuscitation Chapter 24 Transport SECTION II ENVIRONMENTAL CRISES Chapter 27 Multiple Trauma Chapter 28 Drowning and Near Drowning: Submersion Injuries Chapter 29 Burns, Electrical Injuries, and Smoke Inhalation SECTION III LIFE-SUPPORT TECHNOLOGIES Chapter 34 Mechanical Ventilation Chapter 35 Inhaled Gases Chapter 36 Extracorporeal Life Support PART THREE CRITICAL CARE ORGAN SYSTEMS SECTION I RESPIRATORY DISEASE Chapter 40 The Molecular Biology of Acute Lung Injury Chapter 41 Respiratory Physiology Chapter 42 Respiratory Monitoring SECTION II NEUROMUSCULAR DISEASE Chapter 49 Acute Neuromuscular Disease Chapter 50 Chronic Neuromuscular Disease SECTION III NEUROLOGIC DISEASE Chapter 51 Developmental Neurobiology, Neurophysiology,and the PICU Chapter 52 Molecular Biology of Brain Injury Chapter 53 Evaluation of the Comatose Child SECTION IV CARDIAC DISEASE Chapter 62 Cardiac Anatomy Chapter 63 Cardiovascular Physiology Chapter 64 Cardiorespiratory Interactions in Children with Heart Disease SECTION V IMMUNOLOGIC DISEASES Chapter 71 Neurohormonal Control in the Immune System Chapter 72 The Immune System Chapter 73 The Polymorphonuclear Leukocyte in Critical Illness SECTION VI INFECTIOUS DISEASES Chapter 77 Principles of Antimicrobial Therapy Chapter 78 Bacterial Sepsis and Mechanisms of Microbial Pathogenesis Chapter 79 Critical Viral Infections SECTION VII NUTRITIONAL AND GASTROINTESTINAL DISORDERS Chapter 85 Principles of Nutrition and Metabolism Chapter 86 Nutritional Support in the Critically Ill Child Chapter 87 The Acute Abdomen SECTION VIII RENAL, ENDOCRINE, AND METABOLIC DISORDERS Chapter 91 Adrenal Dysfunction Chapter 92 Disorders of Glucose Homeostasis Chapter 93 Disorders of Water, Sodium, and Potassium Homeostasis SECTION IX ONCOLOGIC AND HEMATOLOGIC DISORDERS Chapter 99 Cancer Therapy: Mechanisms, Toxicity, and Ethics in the PICU Chapter 100 Oncologic Emergencies and Complications Index
