Part I. Introductory Chapters on Dementia: 1. Dementia at the bedside Bradley F. Boeve and Bruce L. Miller; 2. Brief cognitive assessment Elena Tsoy, Katherine Possin; 3. Neuropsychiatric symptoms of dementia Yavuz Ayhan, Bruce L Miller; 4. Neuropathology of dementia Eun-Joo Kim, Sarat Vatsavayai and William W. Seeley; 5. Neurotransmitters and neuromodulators in dementia Neus Falgas Martinez, Caroline Lew, Alejandra Sanchez Lopez, Cathrine Petersen and Lea T. Grinberg; 6. Cerebrospinal fluid, molecular neuroimaging, and blood biomarkers of neurodegenerative disease: past, present, and future David N. Soleimani-Meigoon and Gil D. Rabinovici; 7. Magnetic resonance imaging in dementia Chloe Anastassiadis, Howard Rosen and Maria Carmela Tartaglia; 8. Epidemiology and risk-factors for dementia Christina S. Dintinca and Kristine Yaffe; 9. Genetic approaches to neurodegenerative disease Leonel T. Takada and Jennifer Yokoyama; Part II. The Dementias: 10. Alzheimer's disease: preclinical to advanced dementia Neus Falgas Martinez and Raquel Sanchez del Valle Diaz; 11. The behavioral variant of frontotemporal dementia: preclinical to advanced dementia Ignacio Illan-Gala and Bruce L. Miller; 12. Early features of primary progressive aphasia Zachary A. Miller, Gaia C. Santi and Maria Luisa Gorno Tempini; 13. The Cognitive neurology of corticobasal degeneration and progressive supranuclear palsy Suzee E. Lee and Carolyn Fredericks; 14. Mild cognitive impairment across the dementias Ronald C. Peterson; 15. Cognitive disorders of the very old: from clinic to pathology Victor Valcour and Lea T. Grinberg; 16. Posterior cortical atrophy Zeinab Abdi, Emma Harding, Victoria Pelak, Keir X. X. Yong and Sebastian J Crutch; 17. Cognitive and behavioral abnormalities of vascular cognitive impairment Hyemin Jang, Jee Hyang Jeong, Eun-Joo Kim, Duk L. Na and Sang Won Seo; 18. Creutzfeldt-Jakob disease and other prion diseases Igor Prufer Araujo and Michael D. Geschwind; 19. Chronic traumatic encephalopathy Breton M. Asken, David C. Perry and Raquel C. Gardner; 20. Normal pressure hydrocephalus Neill R. Graff-Radford and Benjamin D. Elder; Part iii. Treatment of the Dementias: 21. Treatment of alzheimer's disease Jeffrey L. Cummings; 22. Treatment of frontotemporal dementia Doris Chen, Lawren VandeVrede and Adam L. Boxer; 23. Treatment of dementia with lewy body Bradley F. Boeve; 24. Delirium masquerading as dementia Sara C. LaHue and S. Andrew Josephson; 25. Sleep issues in dementia Sandra Gimenez and Bradley F. Boeve; 26. Caregiving in dementia Jennifer Merrilees, Sarah Dulaney and Robert W. Levenson; 27. Legal Issues in dementia Jalayne Arias, Megan Wright and Ana Tylor.