Preface: Guarino, A.; Quigley, E.M.M.; Walker, W.A.; Composition and Modulation of Intestinal Microbiota; Probiotics: Definition and Taxonomy 10 Years after the FAO/WHO Guidelines: Morelli, L.; Intestinal Microbiota Composition in Children: Buccigrossi, V.; Nicastro, E.; Guarino, A.; Intestinal Microbiota Composition in Adults: Robles Alonso, V.; Guarner, F.; The Intestinal Microbiota and Aging: O'Toole, P.W.; Brigidi, P.; Shaping Intestinal Bacterial Community by TLR and NLR Signaling: Kobayashi, K.S.; Functions and Dysfunctions of Intestinal Microflora; Importance of Early Microbial Colonization for Intestinal Immune Development: Brandtzaeg, P.; Effects of the Intestinal Microbiota on Behavior and Brain Biochemistry: Barrett, E.; Dinan, T.G.; Cryan, J.F.; Quigley, E.M.M.; Shanahan, F.; O'Toole, P.W.; Fitzgerald, G.F.; Stanton, C.; Ross, R.P.; Relationship between Bacterial Colonization of Human Digestive and Respiratory Tract: Lynch, S.V.; Probiotics in the Prevention and Treatment of Diseases in Adults and Children; Probiotics in the Prevention and Treatment of Inflammatory Bowel Diseases in Children: Pigneur, B.; Ruemmele, F.M.; Functional Gastrointestinal Disorders in Children: Indrio, F.; Riezzo, G.; Functional Gastrointestinal Disorders in Adults: Quigley, E.M.M.; Metabolic Syndrome and Obesity in Children: Luoto, R.; Collado, M.C.; Laitinen, K.; Salminen, S.; Isolauri, E.; Metabolic Syndrome and Obesity in Adults: Power, S.E.; Fitzgerald, G.F.; O'Toole, P.W.; Ross, R.P.; Stanton, C.; Quigley, E.M.M.; Murphy, E.F.; Specific Bugs for Specific Diseases; Neonatal Necrotizing Enterocolitis: Neu, J.; Role of Probiotics in Allergies: Berni Canani, R.; Di Costanzo, M.; Nocerino, R.; Pezzella, V.; Cosenza, L.; Granata, V.; Leone, L.; Probiotics in Respiratory Infections: Bruzzese, E.; Lo Vecchio, A.; Ruberto, E.; Probiotics in Food; Are Probiotic Effects Dose-Related? Patton, T.J.; Guandalini, S.; Safety of Probiotics: Hojsak, I.; Shamir, R.; The Future; Age-Related Functional Feeding: A Novel Tool to Improve the Quality of Life: Forssten, S.D.; Roytio, H.; Ibrahim, F.; Ouwehand, A.C.; Use of Microbes to Fight Microbes: Hill, C.; What is the Future for Therapies Derived from the Microbiome (Pharmabiotics)? Rijkers, G.T.; Mulder, L.; Rombouts, F.M.; Akkermans, L.M.A.