A valuable resource for any student majoring in the health sciences, Dr. Grilly's text examines human drug use from historical, societal, and biological perspectives.
This scholarly overview provides a rich foundation for understanding drugs and their usage. In addition to describing basic pharmacological principles, Grilly discusses the general factors behind and approaches for dealing with drug tolerance, dependence, and abuse. By using the most up-to-date research, and by presenting data in concise, jargon-free prose, the author has created one of the most comprehensive and accessible books on the subject.
Information is organized from the general to the specific, beginning with a historical perspective and subsequently moving through drug classifications, approaches to drug tolerance, dependence and abuse, psychological and behavioral effects, pharmacokinetics, mechanisms of action, common side effects, and current issues regarding drugs and their uses.
Auflage
Sprache
Verlagsort
Verlagsgruppe
Zielgruppe
Maße
Höhe: 232 mm
Breite: 178 mm
Dicke: 22 mm
Gewicht
ISBN-13
978-0-205-31831-5 (9780205318315)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Klassifikation
Preface.
1. Psychopharmacology in Perspective.
A Historical Overview of Psychopharmacology.
Predecessors to Modern Pharmacotherapies.
The Psychopharmacological Revolution.
Recreational and Social Drug Use.
2. Basic Principles of Pharmacology.
Drugs and Receptors.
Dose-Response Relationships.
Drug Interactions.
3. Pharmacokinetics.
Drug Absorption.
Routes of Administration.
Drug Distribution.
Metabolism.
Drug Excretion.
Implications of Pharmacokinetics in the Fetus and Neonate.
4. Conduction and Neurotransmission.
The Neuron.
Conduction.
Neurotransmission.
Autoreceptors and Presynaptic Receptors.
Nonsynaptic Diffusion Neurotransmission.
5. Neuroactive Ligands and the Nervous System.
Neurotransmitters, Neuromodulators, and Neurohormones.
Specific Neurotransmitters.
Neurotransmitters and Diet.
Structures and Subsystems of the Nervous System.
Drugs, the Nervous System, and Behavior: A Perspective.
6. Tolerance and Dependence.
What is Tolerance?
Tolerance Mechanisms.
What is Dependence?
General Factors in Treatment for Drug Dependency.
State-Dependent Learning.
7. Psychotropic Drug Classification.
Molecular Structure-Activity Relationships.
Depressant versus Stimulant Classifications.
Drug Use Classification.
Schedule-Controlled Drugs.
8. Sedative-Hypnotics and Anxiolytics.
Alcohol (Ethanol).
Barbiturates and Other Sedative-Hypnotics.
Inhalants: Anesthetic Gases and Solvents.
Anxiolytics.
Buspirone.
Antidepressants as Anxiolytics.
Kava- an Herbal Anxiolytic?
Sedative-Hypnotics and Insomnia.
9. Psychostimulants.
Caffeine.
Amphetamines and Related Drugs.
Cocaine.
Methcathinone.
Treatment of Cocaine and Amphetamine Abuse.
Nicotine, Convulsants, Antidepressants, Pemoline, Modafinil.
Psychostimulants, Learning, and Memory.
10. Opioids (Narcotics) and Their Antagonists.
Endogenous Opioid Peptides and their Receptors.
Typical Opiates.
Behavioral and Physiological Effects of Opiates.
Opioid Pharmacodynamics.
Tolerance and Dependence on Opiates.
Treatment for Opiate Dependence.
The "Overdose" Phenomenon.
Legal Factors in the Narcotics Problem.
Opiate Antagonists: Potential Uses.
11. Psychotomimetics, Psychedelics, and Hallucinogens.
Some General Characteristics of P/P/Hs.
Monoamine-Related P/P/Hs.
Cannabinoids.
Dissociative Anesthetics: Phencyclidine and Ketamine.
Anticholinergics.
Ibogaine.
P/P/Hs: The Human Experience.
12. Antipsychotics.
Biochemical Hypotheses of Schizophrenia.
Present-Day Antipsychotics.
Current Pharmacotherapy for Schizophrenia.
13. Antidepressants and Antimanics.
Biochemical Hypotheses of Affective Disorders.
Pharmacotherapy for Depression.
Pharmacotherapy in Mania and Bipolar Illness.
Non-drug Treatments for Depression.
14. Pharmacotherapy for Miscellaneous Mental Disorders.
Disorders in Children.
Parkinson's Disease.
Tourette's Syndrome.
Epilepsy.
Geriatric Psychopharmacology.
Sexual Dysfunction.
Eating Disorders.
Drug Brand Name Index.
Index.
