In recent years much enthusiasm and energy has been directed  toward the development of human gene therapies, especially for  inherited conditions and cancers. However, current gene transfer  technology is limited in its transduction efficiency and ability to  permanently and safely correct genomic defects. Thus the promise of  gene therapy for these conditions is as yet unrealized. The  progression of gene transfer technology will eventually surmount these  limitations.
  Gene Therapy for Acute and Acquired Diseases includes selected  examples of ongoing studies in molecular genetics that have the  potential to evolve into human therapies for acute illnesses. These  chapters are intended to highlight lesser known applications of gene  therapy for acquired disorders. It is expected that human gene therapy  trials for these conditions will be forthcoming in the near future,  leading to previously unimaginable therapies. Thus, this first-ever  book about gene therapy for acute and acquired diseases is intended to  serve as a glimpse into the future.
 
Auflage
Sprache
Verlagsort
Zielgruppe
Für höhere Schule und Studium
Für Beruf und Forschung
Research
 
Illustrationen
Maße
Höhe: 241 mm
Breite: 160 mm
Dicke: 22 mm
 
Gewicht
ISBN-13
978-0-7923-7268-4 (9780792372684)
 
DOI
10.1007/978-1-4615-1667-5
 
Schweitzer Klassifikation
 
 
1 Rationale for the Use of Gene Therapy for Critical Illness.- 2 Gene Delivery in the ICU.- 3 Non-viral Based Gene Therapy for Pulmonary Disease.- 4 Gene Therapy for Acute Lung Injury.- 5 Gene Therapy for Preservation of Alveolar Endothelial and Epithelial Function.- 6 Gene Therapy for Fibroproliferative Phase ARDS.- 7 Gene Therapy for Asthma.- 8 Gene Therapy for Infectious Diseases.- 9 Gene Therapy for HIV and ABDS-Related Opportunistic Infections.- 10 Gene Therapy for Acute Kidney Diseases.- 11 Gene Therapy Strategies to Augment Contractile Function in Heart Failure.- 12 Gene Therapy for Cerebrovascular Disease and Central Nervous System Trauma.- 13 Gene Therapy for Applications for the Treatment of Acute Inflammatory Conditions.- 14 Facilitation of Organ Transplantation with Gene Therapy.- 15 Cardiac Angiogenesis and Gene Therapy: A Strategy for Myocardial Revascularization.