Brain metabolism; cerebral and spinal cord blood flow; pathophysiology of metabolic brain injury; cerebrospinal fluid; intracranial pressure; the blood brain carrier and cerebral oedema; cerebral blood flow, metabolism and intracranial pressure; neuroradiology; neurophysiologic brain monitoring - evoked potentials; neurophysiologic brain monitoring - electroencephalography; intraoperative fluid management during craniotomy; care of the acutely unstable patient; superatentorial masses - surgical considerations; superatentorial masses - anesthetic considerations; the posterior fossa - surgical considerations; the posterior fossa - anesthetic considerations; cerebral aneurysms and arterio-venous malformations - surgical considerations; cerbral aneurysms - anaesthetic considerations; interventional neuroradiology and the anaesthetic management of patients with arterio-venous malformations; induced hypertension; anaesthesia management of patients undergoing neuroradiologic procedures; anaesthetic management of patients undergoing blood brain barrier disruption; occlusive cerebrovascular disease - medical and surgical considerations; occlusive cerebrovascular disease - anaesthetic considerations; anaesthesia for patients undergoing surgery for seizures; anaesthesia for paediatric neurosurgery; neurosurgical diseases of the spine and spinal cord - surgical considerations; neurosurgical diseases of the spine and spinal cord - anaesthetic considerations; anaesthetic considerations in patients with neuroendocrine disease; post-operative and intensive care; management of severe head injury; multi-system sequelae of severe head injury; spinal cord injury; brain death; ethical considerations in the care of patients with neurosurgical disease.