Section 1 Immunology and Genetics. 1 The Immune Response to Organ Allografts. Manikkam Suthanthiran. 2 Allorecognition Pathways. Nader Najafian and Mohamed H. Sayegh. 3 Costimulation. Elizabeth Ingulli and David M. Briscoe. 4 The HLA System and Histocompatibility Testing for Organ Transplantation. Rene J. Duquesnoy. 5 Gene Polymorphisms and Pharmacogenomics. Robyn Temple-Smolkin, Gilbert J. Burckart and Adriana Zeevi. 6 Genomics and Proteomics as Research Tools. Elaine S. Mansfield and Minnie M. Sarwal. 7 Tolerance: A Review of its Mechanisms in the Transplant Setting. Alan D. Salama. Section 2 Immunosuppression and its Complications. 8 Mechanisms of Action of Immunosuppressive Agents. Alan M. Krensky . 9 Induction and Maintenance Immunosuppression. William E. Harmon. 10 Novel Immunosuppressants. Flavio Vincenti and Ryutaro Hirose. 11 Therapies for the Allosensitized Patient. Alice Peng and Stanley C. Jordan. 12 Infections Post-Transplantation. Michael Green and Marian G. Michaels. 13 Post-Transplant Lymphoproliferative Disorders and Malignancy. Steven A. Webber and Michael Green . 14 Organ Toxicities. Vikas R. Dharnidharka, Carlos E. Araya and Mark R. Benfield. Section 3 Kidney Transplantation . 15 Historical Notes. Vassilios E. Papalois and John S. Najarian . 16 Recipient Characteristics. Sharon M. Bartosh. 17 Evaluation of the Candidate. Uptal D. Patel and Susan E. Thomas . 18 Donor Evaluation, Surgical Technique and Perioperative Management. Zoran Vukcevic, Demetrius Ellis, Mark Bellinger and Ron Shapiro. 19 Pathology of the Kidney Allograft. Arthur H. Cohen. 20 Post-Transplant Management. Jodi M. Smith and Ruth A. McDonald . 21 Outcomes and Risk Factors. Alicia M. Neu and Barbara A. Fivush . Section 4 Liver Transplantation. 22 Historical Notes. Silvio Nadalin, Massimo Malago and Christoph E. Broelsch . 23 Recipient Characteristics. Udeme D. Ekong, Estella M. Alonso and Peter F. Whitington . 24 Evaluation of the Candidate. Binita M. Kamath and Elizabeth B. Rand . 25 Donor Evaluation, Surgical Technique and Perioperative Management. Jean C. Emond, Steven J. Lobritto and Dominique Jan . 26 Pathology of the Liver Allograft. Maria Parizhskaya and Ronald Jaffe . 27 Post-Transplant Management. Kyle Soltys, Robert Squires, Rakesh Sindhi and George V. Mazariegos . 28 Outcomes and Risk Factors. Marc L. Melcher and John P. Roberts . Section 5 Heart Transplantation. 29 Historical Notes. Steven A. Webber and William H. Neches . 30 Recipient Characteristics. Charles E. Canter and David C. Naftel . 31 Evaluation of the Candidate. Gerard J. Boyle . 32 Donor Evaluation, Surgical Technique and Perioperative Management. Frank A. Pigula and Steven A. Webber . 33 Pathology of the Cardiac Allograft. Maria Parizhskaya . 34 Post-Transplant Management. Shelley D. Miyamoto and Biagio A. Pietra. 35 Outcomes and Risk Factors. W. Robert Morrow and Richard E. Chinnock . Section 6 Lung and Heart-Lung Transplantation. 36 Historical Notes. Eric N. Mendeloff. 37 Recipient Characteristics. Eithne F. MacLaughlin. 38 Evaluation of the Candidate. Albert Faro, Gary Visner and George B. Mallory . 39 Donor Evaluation, Surgical Technique and Perioperative Management. Charles B. Huddleston . 40 Pathology of the Lung Allograft. Paul S. Dickman . 41 Post-Transplant Management. Marlyn S. Woo . 42 Outcomes and Risk Factors. Stuart C. Sweet . Section 7 Intestinal Transplantation. 43 Historical Notes. Jorge Reyes. 44 Recipient Characteristics. Jean F. Botha and Debra L. Sudan . 45 Evaluation of the Candidate. Stuart S. Kaufman . 46 Donor Evaluation, Surgical Technique and Perioperative Management. Thomas M. Fishbein and Cal S. Matsumoto . 47 Pathology of the Intestinal Allograft. Maria Parizhskaya and Ronald Jaffe . 48 Post-Transplant Management. Erick Hernandez, Tomoaki Kato, Andreas G. Tzakis and John F. Thompson. 49 Outcomes and Risk Factors. Douglas G. Farmer . Section 8 Special Issues after Pediatric Transplantation. 50 Growth and Puberty. Franz Schaefer . 51 Cognitive Development. Erik Qvist, Hannu Jalanko and Christer Holmberg . 52 Psychosocial Adaptation and Adherence. Eyal Shemesh. 53 Pregnancy. Vincent T. Armenti, Michael J. Moritz and John M. Davison . 54 Gynecologic Issues. Gina S. Sucato and Pamela J. Murray. 55 Transition to Adult Care. Janet McDonagh and Deirdre A. Kelly . Index