Mucosal Delivery of Biopharmaceuticals

Concepts in Mucosal Immunity and Mucosal Vaccines.- Mucoadhesion and Characterization of Mucoadhesive Properties.- Mucus as a Barrier for Biopharmaceuticals and Drug Delivery Systems.- Epithelial Permeation and Absorption Mechanisms of Biopharmaceuticals.- Oral Delivery of Biopharmaceuticals.- Buccal Delivery of Biopharmaceuticals: Vaccines and Allergens.- Pulmonary Delivery of Biopharmaceuticals.- Nasal Delivery of Biopharmaceuticals.- Ocular Delivery of Biopharmaceuticals.- Vaginal Delivery of Biopharmaceuticals.- Nanoparticles-in-Microsphere Oral Delivery Systems (NiMOS) for Nucleic Acid Therapy in the Gastrointestinal Tract.- Bacteria-Based Vectors for Oral Gene Therapy.- Self-Assembled Polysaccharide Nanogels for Nasal Delivery of Biopharmaceuticals.- PheroidT Vesicles and Microsponges for Nasal Delivery of Biopharmaceuticals.- Delivery Strategies for Developing siRNA-Based Vaginal Microbicides.- Delivery Strategies for Developing Vaginal DNA Vaccine Combining Cell-Penetrating Peptides and Jet Injection.- Vaccine Delivery Systems for Veterinary Immunization.- Eligen® Technology for Oral Delivery of Proteins and Peptides.- The RapidMistT System for Buccal Delivery of Insulin.- The Pharmaceutical Development of rhDNase (Dornase Alpha) for the Treatment of Cystic Fibrosis.- Development of the Exubera ^® Insulin Pulmonary Delivery System.- Technosphere®: An Inhalation System for Pulmonary Delivery of Biopharmaceuticals.- ChiSys ^® as a Chitosan-Based Delivery Platform for Nasal Vaccination.- Development of a Cationic Nanoemulsion Platform (Novasorb ^® ) for Ocular Delivery.- Regulatory Aspects and Approval of Biopharmaceuticals for Mucosal Delivery: Quality, Toxicology and Clinical Aspects.