Multicatalyst System in Asymmetric Catalysis

Name: Multicatalyst System in Asymmetric Catalysis
Brand: Wiley
Price: 159.99 EUR
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Jian Zhou(Autor*in)

Wiley (Verlag)

Erschienen am 29. September 2014

712 Seiten

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978-1-118-84700-8 (ISBN)

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Inhalt

Intro
Multicatalyst System in Asymmetric Catalysis
Contents
Preface
Contributors
1 Toward Ideal Asymmetric Catalysis
1.1 Introduction
1.2 Challenges to Realize Ideal Asymmetric Catalysis
1.3 Solutions
1.4 Borrow ideas from Nature
1.5 Conclusion
References
2 Multicatalyst System
2.1 Introduction
2.2 Models of Substrate Activation
2.2.1 The Activation of Electrophiles
2.2.2 The Activation of Nucleophiles
2.2.3 SOMO Catalysis
2.3 Early Examples of the Application of Multicatalyst System in Asymmetric Catalysis
2.4 A General Introduction of Multicatalyst-Promoted Asymmetric Reactions
2.5 Classification of Multicatalyst-Promoted Asymmetric Reactions
2.6 Challenges and Possible Solutions
2.7 Multicatalyst System Versus Multifunctional Catalyst
2.8 Multicatalyst System Versus Additives-Enhanced Catalysis
2.9 Additive-Enhanced Catalysis
2.9.1 Nitrogen-containing Organobase
2.9.2 Inorganic Bases
2.9.3 H2O
2.9.4 Molecular Sieves and Dehydrators
2.9.5 N-oxide, P-oxide, and As-oxide
2.9.6 Alcohols and Phenols
2.9.7 Ammonium Halides and Metal Halides
2.9.8 Amides
2.9.9 Brønsted Acids and Lewis Acids
2.9.10 Two or More Additives Together
2.10 Conclusion
References
3 Asymmetric Multifunctional Catalysis
3.1 Introduction
3.2 Asymmetric Multifunctional Organocatalysis
3.2.1 H-Bond Donor-Tertiary Amine Catalysis
3.2.2 H-Bond Donor-Enamine Catalysis
3.2.3 H-Bond Donor-Phase Transfer Catalysis
3.2.4 H-Bond Donor-Tertiary Phosphine Catalysis
3.2.5 Chiral Phosphoric Acid Catalysis
3.2.6 Asymmetric Bifunctional Salt Catalysis
3.2.7 Miscellaneous
3.3 Asymmetric Hybrid Organo/Metal Catalysis
3.3.1 Brønsted Base/Lewis Acid Bifunctional Catalysis
3.3.2 Lewis Base/Lewis Acid Bifunctional Catalysis
3.3.3 Brønsted Acid/Lewis Acid Bifunctional Catalysis
3.3.4 Enamine/Lewis Acid Bifunctional Catalysis
3.3.5 Hemilable Trisoxazolines
3.4 Asymmetric Multifunctional Multimetallic Catalysis
3.4.1 Asymmetric Multifunctional Heteromultimetallic Catalysis
3.4.2 Asymmetric Multifunctional Homomultimetallic Catalysis
3.5 Anion-Enabled Bifunctional Asymmetric Catalysis
3.5.1 Ammonium Fluorides or Metal Fluorides
3.5.2 Metal Phosphates
3.5.3 Metal Carboxylates
3.5.4 Ammonium or Metal Aryloxides
3.5.5 Hydroxides and Alkoxides
3.5.6 Metal Amides
3.6 Conclusion
References
4 Asymmetric Cooperative Catalysis
4.1 Introduction
4.2 Catalytic Asymmetric Michael Addition Reaction
4.2.1 Combining Multiple Metal Catalysts
4.2.2 Combining Two Distinct Organocatalysts
4.2.3 Combining Metal Catalyst with Organocatalyst
4.3 Catalytic Asymmetric Mannich Reaction
4.3.1 Combining Lewis Acid Catalyst and Brønsted Base Catalyst
4.3.2 Combining Brønsted Acid Catalyst and Lewis Acid Catalyst
4.3.3 Combining Brønsted Acid Catalyst and Secondary Amine Catalyst
4.4 Catalytic Asymmetric Conia-ENE Reaction
4.4.1 Combining Chiral Lewis Acid and Achiral Lewis Acid
4.4.2 Combining Chiral Brønsted Base and Achiral Lewis Acid
4.5 Catalytic Asymmetric Umpolung Reaction
4.5.1 Combining NHC Catalyst and Lewis Acid Catalyst
4.5.2 Combining NHC Catalyst and Brønsted Acid Catalyst
4.6 Catalytic Asymmetric Cyanosilylation Reaction
4.7 -Alkylation Reaction of Carbonyl Compounds
4.7.1 -Alkylation of Carbonyl Compounds using Alcohols as Alkylation Reagents
4.7.2 -Alkylation of Carbonyl Compounds through Benzylic CH Bond Oxidation
4.8 Catalytic Asymmetric Allylic Alkylation Reaction
4.8.1 Combining Achiral Transition Metal with Chiral LUMO-Lowering Catalysis
4.8.2 Combining Chiral Transition Metal Catalysis with Achiral Organocatalyst
4.9 Catalytic Asymmetric Aldol-Type Reaction
4.10 Catalytic Asymmetric (Aza)-Morita-Baylis-Hillman Reaction
4.10.1 Chiral Lewis Base/Achiral Acid Cocatalyzed (aza)-MBH Reaction
4.10.2 Achiral Lewis Base/Chiral Acid Cocatalyzed (aza)-MBH Reaction
4.11 Catalytic Asymmetric Hydrogenation Reaction
4.12 Catalytic Asymmetric Cycloaddition Reaction
4.12.1 [2 + 2] Reaction
4.12.2 [4 + 2] Reaction
4.13 Catalytic Asymmetric NH Insertion Reaction
4.14 Catalytic Asymmetric -Functionalization of Aldehydes
4.15 Miscellaneous Reaction
4.16 Conclusion
References
5 Asymmetric Double Activation Catalysis by Multicatalyst System
5.1 Introduction
5.2 Double Activation by Aminocatalysis and Lewis Base Catalysis
5.3 Asymmetric Double Primary Amine and BrØnsted Acid Catalysis
5.3.1 Diels-Alder (DA)Reaction
5.3.2 Michael Addition
5.3.3 Epoxidation
5.3.4 Miscellaneous Reaction
5.4 Asymmetric Double Metal and BrØnsted Base Catalysis
5.4.1 [3 + 2] Cycloaddition
5.4.2 Aldol Reaction
5.4.3 Miscellaneous Reactions
5.5 Asymmetric H-bond Donor Catalysis and Lewis Base Catalysis
5.6 Sequential Double Activation Catalysis
5.7 Conclusion
References
6 Asymmetric Assisted Catalysis by Multicatalyst System
6.1 Introduction
6.2 Asymmetric Assisted Catalysis within Acids and Bases
6.2.1 Acid Assisted Acid Catalysis
6.2.2 Base Assisted Brønsted Acid Catalysis
6.2.3 Lewis Base Assisted Brønsted Base Catalysis
6.2.4 Acid Assisted Base Catalysis
6.2.5 Miscellaneous
6.3 Modulation of a Metal Complex by a Chiral Ligand
6.3.1 Modulation of a Chiral Metal Complex with a Chiral Ligand
6.3.2 Asymmetric Deactivation, Activation, and Deactivation/Activation
6.3.3 Asymmetric Activation of Racemic Catalysts Bearing Tropos Ligand
6.4 Supramolecular-Type Assisted Catalysis
6.5 Conclusion
References
7 Asymmetric Catalysis Facilitated by Photochemical or Electrochemical Methods
7.1 Introduction
7.2 Catalytic Asymmetric Reaction Facilitated by Photochemical Method
7.2.1 Asymmetric Oxidation Reactions
7.2.2 -Functionalization of Tertiary Amines
7.2.3 -Functionalization of Aldehydes
7.2.4 [2 + 2] Photocycloaddition Reaction
7.2.5 Miscellaneous Reactions
7.3 Catalytic Asymmetric Reactions Facilitated by Electrochemical Method
7.4 Conclusion
References
8 Multicatalyst System Realized Asymmetric Tandem Reactions
8.1 Introduction
8.1.1 Basic Models of MSRATR
8.1.2 Challenges and Solutions for the Development of MSRATR
8.2 Multicatalyst Systems of Homocombination
8.2.1 By Multiple Metal Catalysts
8.2.2 By Multiple Organocatalysts
8.2.3 By Multiple Enzymes
8.3 Hetero Combination System Realized MSRATR
8.3.1 By Combination of Metal and Organocatalysts
8.3.2 By Combination of Metal Catalysis and Biocatalysis
8.3.3 By Combination of Organocatalysis and Biocatalysis
8.4 Conclusion
References
9 Waste-Mediated Reactions
9.1 Introduction
9.2 Historical Background
9.3 Waste-Promoted Single Reactions
9.3.1 Waste Act as a Brønsted Base
9.3.2 By-product as Lewis Base
9.4 By-Products as Acidic Promoter
9.5 Waste-Promoted Tandem Reactions
9.6 Waste-Catalyzed Tandem Reactions
9.7 Conclusions
References
10 Multicatalyst System Mediated Asymmetric Reactions in Total Synthesis
10.1 Introduction
10.2 Application of Multicatalyst System Mediated Single Reactions
10.3 Application of Multicatalyst Mediated Tandem Reaction
10.4 Conclusion
References
Index
EULA

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