Neurodegeneration and Neuroprotection in Parkinson's Disease

Oxidant Stress:J.M.C. Gutteridge and B. Halliwell, Oxidative Stress, Brain Iron, and Neurodegeneration: Basic Principles.P. Jenner and C.W. Olanow, Pathological Evidence for Oxidative Stress in Parkinson's Disease and Related Degenerative Disorders.K. Kieburtz and I. Shoulson, Treatment of Parkinson's Disease with Deprenyl (Selegiline) and Other Mondamine Oxidase Inhibitors.C.W. Olanow and M.B.H. Youdim, Iron and Nuerodegeneration: Prospects for Neuroprotection.R.A. Floyd and J.M. Carney, Nitrone Radical traps (NRTs) Protect in Experimental Neurodegenerative Diseases.M. Flint Beal, Therapeutic Effects of NOS Inhibition in Neuronal Injury. Mitochodrial Toxicity:A.H.V Schapira, Mitochondrial Dysfunction in Neurodegeneration: Prospects for Neuroprotection.Excitatory Neurotoxicity:J.G. Greene and J.T. Greenamyre, Bioenergetics and Exitotoxicity: The Weak Excitotoxic Hypothesis.Calcium Exitatory Toxicity:P. Nicotera and S. Orrenius, Calcium Ions in Necrotic and Apoptotic Cell Death. Trophic Factors:C.A. Altar, S.J. Wiegand, R.M. Lindsay, and J.M. Cedarbaum, Neurotrophic Factors: Towards a Restorative Therapy of Parkinson's Disease.Immune Mechanisms:S.H. Appel, R.G. Smith, and W.D. Le, Immuno-Mediated Cell Death and Neuroprotection in Neurodegenerative Diseases. Apoptosis:W.G. Tatton, M.Y.H. Ju, J. Wadia, and N.A. Tatton, Reduction of Neuronal Apoptosis by Small Molecules: Promise for New Approaches to Neurological Therapy. Subject Index.