Residual Dipolar Couplings

Professor Lishan Yao is an expert in protein solution NMR and molecular dynamics simulation. He has developed several NMR methods combined with MD simulations in studying protein noncovalent interactions (electrostatics, hydrogen bonds, van der Waals, and etc.). He has also developed residual dipolar couplings (RDCs) methods to determine protein structure and conformational dynamics. His research interests focus on studying protein conformational properties and weak interactions, and their impact on protein function.



Beat Voegeli is an expert in nuclear magnetic resonance (NMR) spectroscopy of biomacromolecules. He develops methodology, including the use of residual dipolar couplings (RDCs), for the elucidation of conformation and communication networks within and between proteins and nucleic acids. He received his Ph.D. degree at the Swiss Federal Institute of Technology (ETH) Zuerich, pursued research at the National Institutes of Health in Bethesda, and is currently an associate professor at the University of Colorado at Denver - Anschutz Medical School.