Neuroinflammation and CNS Disorders

List of Contributors vii
Preface xiii
Introduction xv
About the Companion Website xxi
1 Immune Privilege of the Brain 1
Ingo Bechmann and Nicola Woodroofe
2 Innate Immunity in the CNS - A Focus on the Myeloid Cell 9
Craig S. Moore, Bryce A. Durafourt and Jack P. Antel
3 Adaptive Immune Responses in the CNS 37
David Male
4 Ageing and the Immune Response in the CNS 59
Divya D.A. Raj, Bart J.L. Eggen and Hendrikus W.G.M. Boddeke
5 Brain Repair: The Role of Endogenous and Transplanted Neural Stem Cells 89
Marco Bacigaluppi, Erica Butti, Cecilia Laterza, Donatella De Feo, Luca Peruzzotti, Arianna Merlini, Melania Cusimano and Gianvito Martino
6 Neuroinflammation in Alzheimer's, Parkinson's and Huntington's Diseases 111
Magdalena Sastre, Loukia Katsouri, Amy Birch, Alexander Renziehausen, David T. Dexter, Robert R. Crichton and Roberta J. Ward
7 CNS Infections 151
S. Louise Cosby, Sareen Galbraith and Derek Healy
8 Neuroimmunology of Amyotrophic Lateral Sclerosis 185
Jenny S. Henkel, David R. Beers, Weihua Zhao and Stanley H. Appel
9 Demyelinating Disorders of the CNS 211
Laura Peferoen, Moniek Kattenbelt, Lenthe Lodder, Paul van der Valk, Johannes M. van Noort and Sandra Amor
10 Other Autoimmune Disorders: Systemic Lupus Erythematosus, Primary Sj¨ogren's Syndrome, Gluten-related Neurological Dysfunction and Paraneoplastic Neurological Syndromes 235
Marios Hadjivassiliou
11 Inflammation in the Pathogenesis of Depression 261
Thomas J. Connor and Andrew Harkin
12 Immune Responses in the CNS in Epilepsy 289
Jan Bauer, Bethan Lang, Sarosh R. Irani and Annamaria Vezzani
13 Inflammatory Mediators and Dysfunction of the Neurovascular Unit following Ischaemia Reperfusion 317
Philip A. Barber
14 Spinal Cord Injury 339
John C. Gensel
15 Immune Responses to Tumours in the CNS 363
Paul Gielen, Paul van der Valk and Pieter Wesseling
Index 385