Section 1 Mechanisms of Drug Action and Therapeutic Principles 1. Introduction Susan L. Ingram and Lynn Wecker 2. Pharmacodynamics: Receptors and Concentration-Response Relationships JoAnn Trejo, Laura M. Bohn and James Carlton Garrison II 3. Pharmacokinetics Namandje Bumpus and Paul Frederick Hollenberg 4. Pharmacogenomics Larisa Cavallari, Scott A. Mosley and Emily J. Cicali 5. Drug Discovery, Development and Regulation Felix Kim, Lance McMahon, James Barrett, Samuel Obeng and Christopher R. McCurdy Section 2 Chemical Mediators and Drugs Affecting Autonomic and Neuromuscular Synapses 6. Introduction to the Autonomic Nervous System Marsha L. Pierce and Lynn Wecker Cholinergic Drugs 7. Muscarinic Agonists, Cholinesterase Inhibitors and Their Clinical Uses Naoto Hoshi and Frederick J. Ehlert 8. Muscarinic Antagonists and Their Clinical Uses Naoto Hoshi and Frederick J. Ehlert 9. Nicotinic Agonists and Their Clinical Uses Marsha L. Pierce and Lynn Wecker 10. Neuromuscular Blocking Drugs and Nicotinic Antagonists Marsha L. Pierce and Lynn Wecker Adrenergic Drugs 11. Adrenergic Agonists and Their Clinical Uses Javier Cuevas 12. Adrenergic Antagonists and Their Clinical Uses Javier Cuevas Section 3 Drug Treatment for Disorders Affecting the Central Nervous System 13. The Central Nervous System Susan L. Ingram and Lynn Wecker 14. Drug Therapy for Alzheimer's Disease and Other Cognitive Disorders/Dementias Michael S. Jaffee, Steven Trent DeKosky, Meredith Wicklund and Benjamin Albert Chapin 15. Pharmacotherapy of Basal Ganglia Disorders: Parkinson Disease and Huntington Disease Samba Reddy and Juan R. Sanchez-Ramos 16. Drug Therapy for Psychoses and Bipolar Disorder Glenn Catalano, Deborah L. Sanchez, Lynn Wecker and Cory M. Klippel 17. Drug Therapy for Depression and Anxiety Glenn Catalano, Deborah L. Sanchez, Lynn Wecker and Greg Sullivan 18. Drug Therapy for the Management of Attention Deficit-Hyperactivity Disorder Samba Reddy 19. Drug Therapy for Insomnia and the Hypersomnias Miranda Lim and Lynn Wecker 20. Drug Therapy for Managing Obesity and Eating Disorders Charles Rudick 21. Treatment of Seizure Disorders Michael A. Rogawski 22. Drug Therapy for Spasticity Disorders Samba Reddy 23. Ethanol, Other Alcohols and Drugs for Alcohol Use Disorder Jesse D. Hinckley and christian J. Hopfer 24. Illicit Psychoactive Compounds and Substance Use Disorder Jeffrey S. Block and Rex M. Philpot Section 4 Drug Therapy for Pain Management 25. Introduction Susan L. Ingram 26. General Anesthetics Jeffrey J. Pasternak and Tasha L. Welch 27. Local Anesthetics Guy Weinberg and Joshua Edwards 28. Opioid Analgesics Susan L. Ingram and Elena Bagley 29. Nonsteroidal Anti-inflammatory Agents and Acetaminophen Jennelle Durnett Richardson and Jill Fehrenbacher 30. Cannabinoids as Analgesics Jeffrey S. Block, Rex M. Philpot and Lynn Wecker 31. Drug Therapy for Migraine Headache Samba Reddy Section 5 Treatment of Inflammatory, Allergic and Immunologic Disorders 32. Drug Therapy for Gout and Hyperuricemia Angelo Gaffo and Keith Elmslie 33. Drug Therapy for Allergic Reactions Annette Gilchrist and Angela Karash 34. Immunosuppressants for Autoimmune Disorders and Organ Transplantation Kymberly Gowdy, Mythili Chunduru and Jennifer Anne Ferrante 35. Drug Therapy for Rheumatoid Arthritis Michelle Jane Ormseth and Keith Elmslie Section 6 Drug Treatment for Cardiovascular Diseases 36. Introduction to the Regulation of Cardiovascular Function Beth A. Habecker, David A. Taylor, Abdel A. Abdel-Rahman and Steven E. Mansoor 37. Overview of Hypertension Management and Drugs That Decrease Sympathetic Tone James A. McCormick, David A. Taylor and Abdel A. Abdel-Rahman 38. Diuretics and Drugs That Affect Volume and Electrolyte Content James A. McCormick and Abdel A. Abdel-Rahman 39. Drugs Affecting the Renin-Angiotensin- Aldosterone System Vardan T. Karamyan and Abdel A. Abdel-Rahman 40. Calcium Channel Blockers Kelly Karpa and Ryan Wilson 41.
