Cancer Genomics and Proteomics

Genome-Wide Mapping Of RNA Pol-II Promoter Usage In Mouse Tissues By Chip-Seq.- Using Native Chromatin Immunoprecipitation To Interrogate Histone Variant Protein Deposition In Embryonic Stem Cells.- Reduced Representation Bisulfite Sequencing To Identify Global Alteration In The DNA Methylation.- A High-Throughput Microrna Expression Profiling System.- Using Pooled Mir30-Shrna Library For Cancer Lethal And Synthetic Lethal Screens.- Genome-Wide RNA Interference Screening To Identify Regulators Of Epigenetic Silencing Of A Tumor Suppressor Gene.- A Diphtheria Toxin Negative Selection In RNA Interference Screening.- Cancer Metabolism: Crosstalk Between Signaling And O-Glcnacylation.- Targeted Genome Modification Via Triple Helix Formation.- Synthesis Of Stabilized Alpha-Helical Peptides.- Arginine-Grafted Biodegradable Polymer: A Versatile Transfection Reagent For Both DNA And Sirna.- Using Laco Arrays To Monitor DNA Double-Strand Break Dynamics In Live Schizosaccharomyces Pombe Cells.- Zebrafish As A Platform To Study Tumor Progression.- Clonal Screens To Find Modifiers Of Partially Penetrant Phenotypes In C. Elegans .- Serum Profiling Using Protein Microarrays To Identify Disease Related Antigens.- Interrogation Of In Vivo Protein-Protein Interactions Using Transgenic Mouse Models And Stable Isotope Labeling.- New Biophysical Methods To Study The Membrane Activity Of Bcl-2 Proteins.- Purification Of Recombinant 2XMBP Tagged Human Proteins From Human Cells.- Computational Analysis In Cancer Exome Sequencing.- Matrix Factorization Methods For Integrative Cancer Genomics.- Computational Methods For DNA Copy-Number Analysis Of Tumors.