Traumatic Brain Injury, An Issue of Neurosurgery Clinics of North America

Name: Traumatic Brain Injury, An Issue of Neurosurgery Clinics of North America
Brand: Elsevier
Price: 99.99 EUR
Availability: OnlineOnly

Paul M. Vespa Daniel Hirt Geoffrey T. Manley(Autor*in)

Elsevier (Verlag)

1. Auflage

Erschienen am 19. September 2016

100 Seiten

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978-0-323-46320-1 (ISBN)

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Inhalt

Intro
Title page
Table of Contents
Copyright
Contributors
Forthcoming Issues
Erratum
Preface
Past, Present, and Future of Traumatic Brain Injury Research
Key points
Introduction
Epidemiology
Traumatic brain injury research metrics
Secondary injury and targets for pharmacologic trials in traumatic brain injury
Clinical trial design: the failure to translate
Recent progress
Recent pitfalls and challenges
Future directions
Summary
Pathophysiology of Traumatic Brain Injury
Key points
Focal traumatic brain injury
Diffuse traumatic brain injury
Functional changes evoked by traumatic brain injury
Excitotoxicity and ionic flux
Metabolic change
Neuroinflammation
Comorbid factors
Imaging Evaluation of Acute Traumatic Brain Injury
Key points
Introduction
Routine clinical imaging
Imaging protocols for traumatic brain injury
Imaging findings of traumatic brain injuries
Role of advanced imaging techniques
Discussion
Concussion-Mild Traumatic Brain Injury: Recoverable Injury with Potential for Serious Sequelae
Key points
Introduction
Definitions
Epidemiology
Pathophysiology
Clinical diagnosis of the acute concussion
Neuropsychological testing
Acute imaging
Repeat injury
Second impact syndrome
Recovering from injury: balancing rest and exercise
Cognitive restructuring
Postconcussion syndrome
Potential for long-term sequelae
Summary
Cerebral Metabolism and the Role of Glucose Control in Acute Traumatic Brain Injury
Key points
Introduction
Brain glucose metabolism principles
Glucose control in critical illness
Glucose metabolism in traumatic brain injury
Role of Metabolomics in Traumatic Brain Injury Research
Key points
Introduction
Discussion
Summary
Cerebral Edema in Traumatic Brain Injury: Pathophysiology and Prospective Therapeutic Targets
Key points
Introduction
Pathogenesis of cerebral edema
Future treatment targets
Summary
Hypothermia in Traumatic Brain Injury
Key points
Introduction
Treatment options
Complications
Summary
Seizures and the Role of Anticonvulsants After Traumatic Brain Injury
Key points
Introduction
Definitions
Posttraumatic seizures in neuroscience intensive care unit patients
Early posttraumatic seizures are not benign
Impaired percentage alpha variability is associated with poor outcome after traumatic brain injury
Posttraumatic epilepsy
Management of posttraumatic seizures
Patient counseling
The Role of Multimodal Invasive Monitoring in Acute Traumatic Brain Injury
Key points
Introduction
Pathophysiologic rationale
Modalities
Future directions
The Role of Surgical Intervention in Traumatic Brain Injury
Key points
Traumatic brain injury epidemiology and cranial surgery rates
Invasive brain monitoring
Evacuation of intracranial hematomas
Decompressive craniectomy in traumatic brain injury
External ventricular drainage in traumatic brain injury
Surgical management of skull fractures
Posttraumatic cerebrospinal fluid leaks
Posttraumatic hydrocephalus
Cranioplasty
Summary
Repetitive Head Impacts and Chronic Traumatic Encephalopathy
Key points
Introduction
Neuropathology of chronic traumatic encephalopathy
Clinical aspects of chronic traumatic encephalopathy
Summary
Disclosures/funding
Index

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