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This book describes various novel biomarkers for the early diagnosis of gastrointestinal (GI) cancers. It also highlights recent advances in understanding the role of molecular markers and biomarkers, such as volatile biomarkers, serum biomarkers, predictive and prognostic molecular markers for the early detection of GI cancers. Further, it discusses novel biomarkers, including circulating microRNAs, serum microRNA and plasma microRNA in GI cancer.
Dr. Neelapu Nageswara Rao Reddy is currently an Assistant Professor at the Department of Biochemistry and Bioinformatics, Institute of Science, Gandhi Institute of Technology and Management (GITAM) (deemed university), India. He obtained his Master's in Life Science from Pondicherry Central University, and Ph.D. in Evolutionary Bioinformatics from Andhra University, Visakhapatnam, India. His research interests include bioinformatics, cancer, and fungal biology with specialization in drug target discovery, HLA-based peptide vaccine design, genome analysis, phylogenyand evolution. Furthermore, he has expanded his research fields to understanding biochemical mechanisms of stress-induced proteins, structure-function relationship of proteins, and exploring next generation sequencing data to understand traits. He has been a recipient of several fellowships, like CSIR-UGC Junior Research Fellowship; and DAAD Visiting Fellowship, Germany. He has published more than 50 research articles in prestigious peer-reviewed international journals and presented 18 abstracts at various national and international conferences. He has served on the editorial board for a number of national and international journals, and is a member of several international scientific societies and organizations, most importantly, Indian Science Congress & Society of Biological Chemists, India.
Chapter 1. Potential Role of Biomarkers, Biosensors, Technologies and Computational Methods in Early Detection of Gastrointestinal Cancer.- Chapter 2. Biomarkers as the Promising Tools for Early Detection of Gastrointestinal Cancer.- Chapter 3. Development and Evaluation of Biomarkers for Early Detection of Cancer.- Chapter 4. Prognostic Molecular Markers for Gastrointestitinal cancer.- Chapter 5. Metabolic Markers for Early Detection of Gastrointestinal Cancer.- Chapter 6. Current Status of MicroRNA-based Biomarkers for Gastric Cancer.- Chapter 7. Genetic Susceptibility Markers of Gastrointestinal Cancer.- Chapter 8. Approaches For Early Detection Of Gastrointestinal Cancer.- Chapter 9. Biosensors and its Applications for Early Detection of Gastrointestitinal Cancer.- Chapter 10. Application of Nanotechnology in Early Detection of Gastrointestinal Cancer.- Chapter 11. Genetic Marker Identification for the Detection of Early-Onset Gastrointestitinal Cancer Through Genome Wide Association Studies.- Chapter 12. Big Data Analytics to Discover Diagnostics and Therapeutics for Gastrointestitinal Cancer.- Chapter 13. System Biology Approach for Early Prognosis of Gastrointestinal Cancer.
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