1. Patient Assessments, Laboratory Interpretation, Clinical Concepts, Patient Management, Practice Management and Risk Reduction: This chapter introduces/reviews/updates patient assessments, laboratory interpretation, musculoskeletal emergencies, healthcare paradigms; the common and important conditions hemochromatosis and hypothyroidism are also included in this chapter since these need to be considered on a frequent basis in clinical practice 1
2. Wellness Promotion & Re-Establishing the Foundation for Health: Reviewed here are diet, lifestyle, psychosocial health, and-given the pervasiveness of persistent organic pollutants and their increasingly recognized clinical importance-an introduction to environmental medicine 187
3. Basic Concepts and Therapeutics in (Nondrug) Musculoskeletal Care and Integrative Pain Management: Nonpharmacologic management of musculoskeletal problems is preferred over pharmacologic (e.g., NSAID, Coxib, steroid, opioid) management because of the collateral benefits, safety, and cost-effectiveness associated with manual, dietary, botanical, and nutritional treatments. A brief discussion of the current crisis in musculoskeletal medicine is provided for contextualization and emphasis of the importance of expanding clinicians' knowledge of effective nondrug treatments 243
4. The Major Modifiable Factors in Sustained Inflammation: Major components of the "Functional Inflammology Protocol" are reviewed here, from concepts and molecular biology to an emphasis on practical clinical applications
1) Food & Basic Nutrition 307
2) Infections: Dysbiosis / Viral 396 / 540
3) Nutritional Immunomodulation 609
4) Dysmetabolism, Mitochondrial Dysfunction, ERS/UPR, mTOR 622
5) Special Considerations: Sleep, Sociopsychology, Stress, Surgery 674
6) Endocrine Imbalances 688
7) Xenobiotic Immunotoxicity 699
303
5. Clinical Applications
1) Hypertension 727
2) Diabetes Mellitus 819
3) Migraine & Headaches 863
4) Fibromyalgia 901
5) Allergic Inflammation 984
6) Rheumatoid Arthritis 1019
7) Psoriasis and Psoriatic Arthritis 1038
8) Systemic Lupus Erythematosus 1053
9) Scleroderma & Systemic Sclerosis 1074
10) Vasculitic Diseases 1094
11) Spondyloarthropathies & Reactive Arthritis 1108
12) Sjögren Syndrome/Disease 1119
13) Raynaud's Syndrome/Phenomenon/Disorder 1127
14) Clinical Notes on Additional Conditions: Behçet's Disease, Sarcoidosis, Dermatomyositis and Polymyositis 1131
713
Index & Appendix 1154
