Mechanisms and Consequences of Proton Transport

Structure and Function of H,K-ATPase - Molecular Basis for Drug Targets.- 1. The Gastric H,K-ATPase.- 2. Human Nongastric H,K-ATPase: Current View On Structure and Functional Properties.- 3. Functional Consequences of Subunit Interactions in Na,K- and H,K-ATPases.- 4. HKc? Encodes Ouabain-Insensitive H,K-ATPase in Surface Cells of Rat Distal Colon.- 5. Molecular Diversity and Regulatory Heterogeneity of H,K-ATPases in Kidney.- 6. Mutational Analysis of Gastric Proton Pump, ?- and ß-Subunits.- 7. Structure-Activity Relationships of Na,K-ATPase and H,K-ATPase.- 8. The Effect of Mutations Within a Cluster of Homologous Amino Acids Present in the M5, M6 and M8 Transmembrane Regions of the H,K-ATPase.- Helicobacter Pylori and Mucosal Protection.- 9. Host-Specific H. pylori Inhibition of H,K-ATPase ? Subunit Gene Expression.- 10. H+, K+-ATPase, the Dominant Gastric Autoantigen In Helicobacter pylori Infection.- 11. The Gastric H/K ATPase in the Pathogenesis of Autoimmune Gastritis.- 12. Duodenal Protection: Influence of Melatonin and Other Intestinal Transmitters on Duodenal Bicarbonate Secretion and Enterocyte Signaling.- 13. Role of Cytokines in Helicobacter pylori-Induced Gastric Epithelial Cell Matrix Metalloproteinase Secretion and Activation.- 14. HCI Causes Less Intracellular Acidification in Surface Epithelial Cells of Isolated Necturus Gastric Mucosa than Other Inorganic Acids.- 15. Ethanol Increases Intracellular Free Calcium, Closes Gap Junctions and Decreases Cell Volume in Primary Cultured Rabbit Gastric Epithelial Cell Monolayers.- 16. Induction of Small Intestinal Damage by Inhibition of Both NO Synthase and COX-2.- 17. Role of Protein Kinases on Acid-Induced Duodenal Bicarbonate Secretion in Rats.- 18. Acid Induces Duodenal Epithelial Acidification andHCO3-" Secretion via Activation of the Na+:HC03-" Cotransporter and CFTR in Mice.- Gene Targeting Mouse - Mechanisms of Acid Secretion and Cell Proliferation.- 19. Insights into the Cell Biology, Development and Pathology of the Gastric Mucosa Revealed in Gastric H/K ATPase and Gastrin-Deficient Mice.- 20. Genetically Engineered Animal Models: Physiological Studies with Gastrin in Transgenic Mice.- 21. Gastric Cytoprotection by Prostaglandin E2 - Relation to EP Receptor Subtypes.- 22. Gastric Mucus Accumulation is Reduced in Helicobacter pylori pylori Infected Transgenic Mice Expressing the Human a-l,3/4-Fucosyltransferase in Surface Epithelial Cells.- Signal Transduction in the Parietal Cell - Pathway to Activation.- 23. New Insights into Second Messenger Regulation of Parietal Cell Function by Novel Downstream Signaling Proteins.- 24. Functional Role of Protein Kinase B/Akt in Gastric Acid Secretion.- 25. Permeabilized Gastric Gland Models - A New Strategy for Analyzing Parietal Cell Signal Transduction.- 26. Parietal Cell Volume Regulation During Acid Secretion.- 27. Characterization, Regulation and Localization of the Gastric CI- Channel Associated with Gastric Acid Secretion.- 28. Identification of Potassium Channels Associated with H,K-ATPase in the Parietal Cell.- 29. Kir2.1 K+ Channels of the Gastric Parietal Cell.- 30. Kinetics of Activation of H+ Secretion by Secretagogues in Relation to Changes in [Ca2+]i in Isolated Gastric Glands.- 31. Measurement of Intracellular Calcium and Gastric Acid Secretion in Real Time Using Fluorescent Probes.- 32. Tissue and Cell Distribution of Parchorin, a Chloride Intracellular Channel-Related Protein.- Cytoskeleton and Membrane Trafficking - the Gastric Parietal Cell as a Model.- 33. Scanning EM Studies ofGastric Oxyntic Cells with Special Reference to the Translocation of Tubulovesicular System towards the Intracellular Canaliculus.- 34. 3-Dimensional Modeling of the Gastric Parietal Cell.- 35. Pharmacological Control of Gastric Acid Secretion via the Apical Membrane of Parietal Cells in Dogs.- 36. The Cytoskeleton as a Modulator of Gastric Secretion.- 37. Clathrin and Associated Proteins on Tubulovesicles and Apical Membranes of Parietal Cells.- 38. Rab11 Interacting Proteins as Regulators of Parietal Cell Apical Recycling: Lessons from the Master.- 39. Regulation of Acid Secretion and Mucosal Permeability by F-actin in the Bullfrog Gastric Mucosa.- 40. Fluid Dynamics of the Excretory Flows of Zymogenic and Mucinous Contents in Rat Gastric Glands Processed by High Pressure Freezing/Freeze Substitution, with Special Reference to the Secretory Dynamics of Phospholipase A2 And Phospholipase Cyl.